HOXB1 Antibody
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中文名稱(chēng)：HOXB1兔多克隆抗體
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貨號(hào)：CSB-PA803064
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規(guī)格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA803064(HOXB1 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：
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別名：HCFP3 antibody; Homeo box 2I antibody; Homeo box B1 antibody; Homeobox 2I antibody; Homeobox B1 antibody; Homeobox protein Hox B1 antibody; Homeobox protein Hox-2I antibody; Homeobox protein Hox-B1 antibody; Homeobox protein HoxB1 antibody; Homeobox2I antibody; HomeoboxB1 antibody; HOX 2 antibody; Hox 2.9 antibody; HOX 2I antibody; HOX B1 antibody; HOX2 antibody; Hox2.9 antibody; HOX2I antibody; HOXB 1 antibody; HOXB1 antibody; HOXB1 protein antibody; HXB1_HUMAN antibody; MGC116843 antibody; MGC116844 antibody; MGC116845 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Fusion protein of Human HOXB1
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:2000-1:5000 IHC 1:25-1:100 -
Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.
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基因功能參考文獻(xiàn)：
- This is the first disease-associated HOXB1 mutation with a likely loss-of-function effect suggesting that all HOXB1 variants reported so far also have severe impact on activity of this transcriptional regulator PMID: 27144914
- findings revealed a novel homozygous mutation p.Arg230Trp (c.688C>T) within the HOXB1 gene of three members of a Turkish family with hereditary congenital facial paresis (HCFP3) PMID: 27640920
- HOXB1 functions as a tumor suppressor, regulated by miR-3175 in glioma. PMID: 26565624
- The resulting phenotype includes bilateral facial palsy, hearing loss, and strabismus and correlates extensively with the previously reported Hoxb1(-/-) mouse phenotype. PMID: 22770981
- Hoxb1 Expression Induces Cell Fate Changes in the Trunk Neural Tube. PMID: 21433221
- analysis of a tethered-hopping model for protein-DNA binding and unbinding based on Sox2-Oct1-Hoxb1 ternary complex simulations PMID: 20371328
- Data show that inducible Hox genes are selectively sensitive to the inhibition of actin polymerization and that actin polymerization is required for the assembly of a transcription complex on the regulatory region of the Hox genes. PMID: 19477923
- It is unlikely that HoxB1 plays a significant role in the genetic predisposition to autism. PMID: 11840501
- UTX directly binds to the HOXB1 locus and is required for its activation PMID: 17713478
- HoxB1 interacts with Pax6 and enhances its transcriptional activity. This interaction was modeled on a demonstrated interaction between zebrafish Pax6 and human HoxB1. PMID: 11069920
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相關(guān)疾病：Facial paresis, hereditary congenital, 3 (HCFP3)
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亞細(xì)胞定位：Nucleus.
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蛋白家族：Antp homeobox family, Labial subfamily
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數(shù)據(jù)庫(kù)鏈接：
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