HCFC1R1 Antibody, HRP conjugated

說明書

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) HCFC1R1 Polyclonal antibody
Uniprot No.：

Q9NWW0
基因名：

HCFC1R1
別名：

HCF 1 beta propeller interacting protein antibody; HCF-1 beta-propeller-interacting protein antibody; HCF1 beta propeller interacting protein antibody; HCFC1R1 antibody; Host cell factor C1 regulator 1 (XPO1 dependent) antibody; Host cell factor C1 regulator 1 antibody; HPIP antibody; HPIP_HUMAN antibody; Inhibitor of four 2 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Host cell factor C1 regulator 1 protein (1-119AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Regulates HCFC1 activity by modulating its subcellular localization. Overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm. HCFC1R1-mediated export may provide the pool of cytoplasmic HCFC1 required for import of virion-derived VP16 into the nucleus.
基因功能參考文獻：
1. HPIP overexpression is an independent predictor of platinum-based chemotherapy resistance in epithelial ovarian neoplasms. PMID: 27818289
2. HPIP promotes thyroid cancer cell growth, migration and epithelial mesenchymal transformation through activating PI3K/AKT signaling pathway. PMID: 26463629
3. HPIP is upregulated in colorectal cancer and regulates colorectal cancer cell proliferation, apoptosis and invasion PMID: 25800793
4. HPIP regulates HCF-1 activity by modulating its subcellular localization PMID: 12235138
亞細胞定位：

Cytoplasm. Nucleus. Note=Shuttles between the nucleus and cytoplasm in a CRM1-dependent manner.
組織特異性：

Widely expressed.
數(shù)據(jù)庫鏈接：

HGNC: 21198

KEGG: hsa:54985

UniGene: Hs.423103

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