Gp2 Antibody, FITC conjugated
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中文名稱：Gp2兔多克隆抗體, FITC偶聯(lián)
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貨號：CSB-PA880511LC01MO
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Mus musculus (Mouse) Gp2 Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：Gp2 antibody; Pancreatic secretory granule membrane major glycoprotein GP2 antibody; Pancreatic zymogen granule membrane protein GP-2 antibody
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宿主：Rabbit
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反應(yīng)種屬：Mouse
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免疫原：Recombinant Mouse Pancreatic secretory granule membrane major glycoprotein GP2 protein (22-531AA)
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免疫原種屬：Mus musculus (Mouse)
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標(biāo)記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情
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功能：Functions as an intestinal M-cells transcytotic receptor specific of type-I-piliated bacteria that participate in the mucosal immune response toward these bacteria. At the apical membrane of M-cells binds fimH, a protein of the bacteria type I pilus tip. Internalizes bound bacteria, like E.coli and S.typhimurium, from the lumen of the intestine and delivers them, through M-cells, to the underlying organized lymphoid follicles where they are captured by antigen-presenting dendritic cells to ellicit a mucosal immune response.
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基因功能參考文獻(xiàn)：
- GP2 is a popular secretory product released from mucous glands and secretory cells and may support defense mechanisms against pathogenic bacteria in the tubular organs open to the external milieu. PMID: 28003582
- GP2-expressing cells in paranasal sinuses are in the lineage of goblet cells. PMID: 25355440
- Tightly linked to homologue THP. A Gp2 knockout mouse was established which does express THP. PMID: 15325280
- unlikely that GP2 serves a major intracellular role within the acinar cell, may be active after it is secreted PMID: 15385539
- glycoprotein 2 (GP2), specifically expressed on the apical plasma membrane of M cells among enterocytes, serves as a transcytotic receptor for mucosal antigens PMID: 19907495
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亞細(xì)胞定位：Zymogen granule membrane; Lipid-anchor, GPI-anchor. Secreted. Cell membrane; Lipid-anchor, GPI-anchor. Apical cell membrane; Lipid-anchor, GPI-anchor. Membrane raft; Lipid-anchor, GPI-anchor. Endosome.
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組織特異性：Specifically expressed by M (microfold) cells which are atypical epithelial cells of the intestine.
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數(shù)據(jù)庫鏈接：
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