GPSM3 Antibody, HRP conjugated
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中文名稱：GPSM3兔多克隆抗體, HRP偶聯
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貨號：CSB-PA896517LB01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) GPSM3 Polyclonal antibody
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Uniprot No.：
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基因名：GPSM3
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別名：Activator of G-protein signaling 4 antibody; AGS4 antibody; C6orf9 antibody; G protein signalling modulator 3 (AGS3 like; C. elegans) antibody; G-protein signaling modulator 3 (AGS3-like; C. elegans) antibody; G-protein-signaling modulator 3 antibody; G18 antibody; G18.1a antibody; G18.1b antibody; G18.2 antibody; Gpsm3 antibody; GPSM3_HUMAN antibody; NG1 antibody; OTTHUMP00000029351 antibody; Protein G18 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human G-protein-signaling modulator 3 protein (1-160AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：HRP
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
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靶點詳情
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功能：Interacts with subunit of G(i) alpha proteins and regulates the activation of G(i) alpha proteins.
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基因功能參考文獻：
- role for GPSM3 in neutrophil migration toward proinflammatory chemoattractants LTB4 and CXCL8-a discovery that helps strengthen the association between the promoter-weakening GPSM3 SNP rs204989 and a reduced risk of rheumatoid arthritis PMID: 27307211
- Genetic variations in GPSM3 which are associated with protection from rheumatoid arthritis affect its transcript abundance. PMID: 26821282
- findings suggest that GPSM3 acts as a direct negative regulator of NLRP3 function. PMID: 25271165
- Phosphorylation of GPSM3 by a proline-directed serine/threonine kinase and the resultant association of 14-3-3 is the first description of post-translational regulation of GPSM3 subcellular localization PMID: 22843681
- GPSM3 increases Gbeta stability until formation of the Gbetagamma dimer, including association of the Gbeta-GPSM3 complex with phosducin-like protein PhLP and T-complex protein 1 subunit eta (CCT7), two known chaperones of neosynthesized Gbeta subunits. PMID: 22167191
- AGS4-Galpha(i) complexes directly couple to a G-protein-coupled receptor and may serve as substrates for agonist-induced G-protein activation. PMID: 20452976
- Mutational analysis of the role of GoLoco motifs in guanine nucleotide dissociation inhibitor activity of G18 protein. PMID: 14656218
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亞細胞定位：Cytoplasm.
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組織特異性：Expressed in heart, placenta, lung and liver.
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數據庫鏈接：
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