GP9 Antibody, Biotin conjugated
-
中文名稱：GP9兔多克隆抗體, Biotin偶聯
-
貨號：CSB-PA009690LD01HU
-
規格：￥880
-
其他：
產品詳情
-
產品名稱：Rabbit anti-Homo sapiens (Human) GP9 Polyclonal antibody
-
Uniprot No.：
-
基因名：
-
別名：GP9; Platelet glycoprotein IX; GP-IX; GPIX; Glycoprotein 9; CD antigen CD42a
-
宿主：Rabbit
-
反應種屬：Human
-
免疫原：Recombinant Human Platelet glycoprotein IX protein (17-88AA)
-
免疫原種屬：Homo sapiens (Human)
-
標記方式：Biotin
-
克隆類型：Polyclonal
-
抗體亞型：IgG
-
純化方式：>95%, Protein G purified
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
-
應用范圍：ELISA
-
Protocols：
-
儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
-
功能：The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib.
-
基因功能參考文獻：
- Case Report: suggest that alloantibodies directed against Cab4b, the first human platelet antigen carried by glycoprotein IX, can induce severe neonatal thrombocytopenia. PMID: 28561420
- factor XI is localized to GPIb in membrane rafts and this association is important for promoting the activation of factor XI by thrombin on the platelet surface PMID: 12517745
- Raft association and cytoskeletal linkage of the platelet GPIb-IX-V complex are interrelated and are required for optimal receptor function, by attracting signaling proteins and membrane skeletal association allows proteins to move to new locations. PMID: 19874464
- the putative convex surface of the LRR domain in GPIX is sufficient, in the context of full-length subunit, to mediate its association with GPIbbeta PMID: 19566547
- Novel nonsense mutation is associated with Bernard-Soulier syndrome. PMID: 12447957
- findings indicate that the Ala14-->Thr mutation in the transmembrane region of GP IX does not induce intracellular GP Ib/IX complex degradation, but prevents its insertion in the cytoplasmic membrane of platelets and CHO cells PMID: 15351858
- the first non-Caucasian Turkish Bernard-Soulier syndrome case due to GPIX N45S and is likely the result of a recurrent mutational event. PMID: 17804902
- Findings point to a role of the GPIb-V-IX complex intrinsic to megakaryocytes at the stage of proplatelet formation and suggest a functional link with the underlying microtubular cytoskeleton in platelet biogenesis. PMID: 19377075
- Homozygous missense mutation in position 1829 (A(R)G) of the GPIX gene causes Bernard-Soulier syndrome in a Swiss family. PMID: 19404517
顯示更多
收起更多
-
相關疾病：Bernard-Soulier syndrome (BSS)
-
亞細胞定位：Membrane; Single-pass type I membrane protein.
-
數據庫鏈接：
Most popular with customers
-
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
-
