GOLGA3 Antibody

中文名稱：

GOLGA3兔多克隆抗體
貨號：

CSB-PA600096LA01HU
規(guī)格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA600096LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA600096LA01HU at dilution of 1:100

Immunofluorescent analysis of HepG2 cells using CSB-PA600096LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) GOLGA3 Polyclonal antibody
Uniprot No.：

Q08378
基因名：

GOLGA3
別名：

GOLGA3Golgin subfamily A member 3 antibody; Golgi complex-associated protein of 170 kDa antibody; GCP170 antibody; Golgin-160 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Golgin subfamily A member 3 protein (217-405AA)
免疫原種屬：

Homo sapiens (Human)

標(biāo)記方式：

Non-conjugated

本頁面中的產(chǎn)品，GOLGA3 Antibody (CSB-PA600096LA01HU)，的標(biāo)記方式是Non-conjugated。對于GOLGA3 Antibody，我們還提供其他標(biāo)記。見下表：

標(biāo)記方式	貨號	產(chǎn)品名稱	應(yīng)用
HRP	CSB-PA600096LB01HU	GOLGA3 Antibody, HRP conjugated	ELISA
FITC	CSB-PA600096LC01HU	GOLGA3 Antibody, FITC conjugated
Biotin	CSB-PA600096LD01HU	GOLGA3 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, IHC, IF

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

功能：

Golgi auto-antigen; probably involved in maintaining Golgi structure.
基因功能參考文獻：
1. The golgin-160 binds directly to the third intracellular loop of beta1AR and that this binding depends on three basic residues in this loop. PMID: 24566136
2. Golgi protein golgin160 recruits dynein to Golgi membranes. PMID: 22814606
3. A common epitope of proteins golgin-160, voltage-gated potassium channel and disulfide isomerase was identified by screening with autoantibodies of a type 1 diabetic patient PMID: 20170975
4. NH2 terminal domain of Golgin 160 has a role in nuclear transport and Golgi apparatus localization PMID: 12130652
5. results indicate that GCP16 is the acylated membrane protein, associated with GCP170, and possibly involved in vesicular transport from the Golgi to the cell surface PMID: 14522980
6. Caspase-resistant GOLGA3 disrupts apoptosis induced by secretory pathway stress and ligation of death receptors. PMID: 15829563
7. golgin-160 assosiates in an isoform-specific manner with the Golgi-associated protein PIST PMID: 15951434
8. GCP60 interacts preferentially with one of the golgin-160 caspase cleavage fragments (residues 140-311). This strong interaction prevented the golgin-160 fragment from accumulating in the nucleus when this fragment and GCP60 were overexpressed. PMID: 16870622
9. golgin-160 may promote efficient surface delivery of a subset of cargo molecules PMID: 17118120
10. nuclear translocation of golgin-160-(140-311) is a highly coordinated event regulated not only by cleavage of the golgin-160 head but also by the oxidation state of GCP60 PMID: 17711851
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亞細(xì)胞定位：

Cytoplasm. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein.
組織特異性：

Expressed in all tissues tested. Expressed in liver, testis, lung, heart, salivary gland and kidney.
數(shù)據(jù)庫鏈接：

HGNC: 4426

OMIM: 602581

KEGG: hsa:2802

STRING: 9606.ENSP00000204726

UniGene: Hs.507333

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