GIMAP4 Antibody

中文名稱：

GIMAP4兔多克隆抗體
貨號：

CSB-PA885732LA01HU
規格：

￥440
圖片：
Immunofluorescence staining of HepG2 cells with CSB-PA885732LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) GIMAP4 Polyclonal antibody
Uniprot No.：

Q9NUV9
基因名：

GIMAP4
別名：

FLJ11110 antibody; GIMA4_HUMAN antibody; Gimap4 antibody; GTPase IMAP family member 4 antibody; GTPase IMAP family member 4 antibody; hIAN1 antibody; HIMAP4 antibody; Human immune associated nucleotide 1 antibody; IAN-1 antibody; IAN1 antibody; IMAP4 antibody; Immunity associated nucleotide 1 protein antibody; Immunity associated protein 4 antibody; Immunity-associated nucleotide 1 protein antibody; Immunity-associated protein 4 antibody; MSTP062 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human GTPase IMAP family member 4 protein (5-101AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，GIMAP4 Antibody (CSB-PA885732LA01HU)，的標記方式是Non-conjugated。對于GIMAP4 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA885732LB01HU	GIMAP4 Antibody, HRP conjugated	ELISA
FITC	CSB-PA885732LC01HU	GIMAP4 Antibody, FITC conjugated
Biotin	CSB-PA885732LD01HU	GIMAP4 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IF

推薦稀釋比：

Application	Recommended Dilution
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

During thymocyte development, may play a role in the regulation of apoptosis. GTPase which exhibits a higher affinity for GDP than for GTP.
基因功能參考文獻：
1. GIMAP4 regulates secretion of cytokines in early differentiating human CD4(+) T helper lymphocytes and in particular the secretion of interferon-gamma also affecting its downstream targets. PMID: 25287446
2. Genome-wide association study identifies GIMAP as a novel susceptibility locus for Behcet's disease PMID: 23041938
3. molecular and genetic properties; expression in resting T- and B-cells and decreased expression during lymphocyte activation PMID: 11964296
4. GIMAP1 and GIMAP4 genes are up-regulated by IL-12 and other Th1 differentiation-inducing cytokines in cells induced to differentiate toward Th1 lineage and down-regulated by IL-4 in cells induced to Th2. PMID: 18701445
亞細胞定位：

Cytoplasm, cytosol.
蛋白家族：

TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, AIG1/Toc34/Toc159-like paraseptin GTPase family, IAN subfamily
組織特異性：

Highly expressed in spleen and peripheral blood leukocytes that contain mostly T- and B-lymphocytes. Expressed specifically in resting T- and B-lymphocytes and expression significantly decreases during B- or T-lymphocyte activation. Expressed at lower lev
數據庫鏈接：

HGNC: 21872

OMIM: 608087

KEGG: hsa:55303

STRING: 9606.ENSP00000255945

UniGene: Hs.647101

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