GGPS1 Antibody
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中文名稱：GGPS1兔多克隆抗體
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貨號：CSB-PA009393GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：GGPS1
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別名：(2E antibody; 6E)-farnesyl diphosphate synthase antibody; Dimethylallyltranstransferase antibody; Farnesyl diphosphate synthase antibody; Farnesyltranstransferase antibody; Geranylgeranyl diphosphate synthase 1 antibody; Geranylgeranyl diphosphate synthase antibody; Geranylgeranyl pyrophosphate synthase antibody; Geranylgeranyl pyrophosphate synthetase antibody; Geranyltranstransferase antibody; GGPP synthase antibody; GGPP synthetase antibody; GGPPS antibody; GGPPS_HUMAN antibody; GGPPS1 antibody; GGPPSase antibody; GGPS1 antibody; OTTHUMP00000036073 antibody; OTTHUMP00000216161 antibody; OTTHUMP00000216163 antibody; OTTHUMP00000216164 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human GGPS1
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins.
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基因功能參考文獻：
- results may support a model in which accumulation of susceptibility variants (including some in relevant genes, notably GGPS1) may lead to a possible genetic component of predisposition to atypical femoral fractures. PMID: 28467865
- GGPPS1 may play a critical role during the development of HCC from cirrhosis and is of clinical significance for predicting biological character of HCC. PMID: 24716791
- Egr-1 most likely does not induce the constitutive activation of Erk1/2 through its target gene GGPS1. PMID: 23478574
- the Egr-1/GGPPS/Erk1/2 pathway is responsible for insulin resistance during hyperinsulinism PMID: 21321112
- these results reveal a new EGR-1/GGPPS/MAPK signaling pathway that controls cigarette smoke-induced pulmonary inflammation. PMID: 21224049
- Study suggested that GGPS1 -8188A ins/del polymorphism may confer susceptibility to femoral neck BMD response to bisphosphonate therapy in Korean women. PMID: 20191015
- crystal structure; it reveals that three dimers join together to form a propeller-bladed hexameric molecule with a mass of approximately 200 kDa PMID: 16698791
- Farnesyltranstransferase mutations are associated with lonafarnib resistance PMID: 17536018
- results indicate that the active form of GGPS in the solution is an octamer rather than hexamer or dimer PMID: 17646172
- Evidence for a non-membrane bound isoform of geranylgeranyl diphosphate synthase 1 in rat. PMID: 8419360
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亞細胞定位：Cytoplasm.
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蛋白家族：FPP/GGPP synthase family
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組織特異性：Abundantly expressed in testis. Found in other tissues to a lower extent.
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數據庫鏈接：
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