GANAB Antibody
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中文名稱：GANAB兔多克隆抗體
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貨號：CSB-PA008333
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規格：￥1090
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圖片：
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Western Blot analysis of LOVO cells using Glucosidase IIα Polyclonal Antibody
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：Alpha glucosidase II alpha subunit antibody; Alpha-glucosidase 2 antibody; G2AN antibody; GANAB antibody; GANAB_HUMAN antibody; Glu II antibody; Glucosidase alpha neutral AB antibody; Glucosidase II alpha antibody; Glucosidase II subunit alpha antibody; GluII antibody; KIAA0088 antibody; Neutral alpha glucosidase AB antibody; Neutral alpha glucosidase AB precursor antibody; Neutral alpha-glucosidase AB antibody
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宿主：Rabbit
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反應種屬：Human,Mouse
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免疫原：Synthesized peptide derived from the Internal region of Human Glucosidase IIα.
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：WB, IHC, ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:5000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Catalytic subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins. Required for PKD1/Polycystin-1 and PKD2/Polycystin-2 maturation and localization to the cell surface and cilia.
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基因功能參考文獻：
- Case Report: GANAB mutation leading to autosomal dominant polycystic kidney disease. PMID: 28784653
- Mutations in GANAB gene is associated with Autosomal-Dominant Polycystic Kidney and Liver Disease. PMID: 27259053
- The high frequency of glucosidase II overexpression, which to the best of our knowledge has not been previously described, indicates its crucial roles in lung tumorigenesis and is thus a valuable biomarker PMID: 24008518
- Loss of the tumor suppression function of Hsp60 or GANAB contribute to aggressive cancers. PMID: 21642380
- In males being treated for infertility, neutral alpha-glucosidase activity correlated with the percentage of sperm DNA fragmentation. PMID: 19737279
- the apparent occurrence of an unusual TG 3' splice site in intron 18 is discussed PMID: 17672918
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相關疾病：Polycystic kidney disease 3 (PKD3)
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亞細胞定位：Endoplasmic reticulum. Golgi apparatus. Melanosome.
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蛋白家族：Glycosyl hydrolase 31 family
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組織特異性：Detected in placenta. Isoform 1 and isoform 2 are expressed in the kidney and liver.
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數據庫鏈接：
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