FUZ Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) FUZ Polyclonal antibody
Uniprot No.：

Q9BT04
基因名：

FUZ
別名：

FLJ22688 antibody; fuz antibody; FUZZY_HUMAN antibody; Fy antibody; Protein fuzzy homolog antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Protein fuzzy homolog protein (280-404AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Probable planar cell polarity effector involved in cilium biogenesis. May regulate protein and membrane transport to the cilium. Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies. May regulate the morphogenesis of hair follicles which depends on functional primary cilia.
基因功能參考文獻：
1. results in vitro show that FUZ is responsible for non-small-cell lung cancer (NSCLC) progression and metastasis, suggesting that FUZ can be a potential therapeutic target for NSCLC. PMID: 29421438
2. Data propose that mutations in Fuzzy may account for a subset of neural tube defects in humans. PMID: 21840926
亞細胞定位：

Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, cilium basal body.
蛋白家族：

Fuzzy family
數據庫鏈接：

HGNC: 26219

OMIM: 610622

KEGG: hsa:80199

STRING: 9606.ENSP00000313309

UniGene: Hs.288800

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