FTCD Antibody
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中文名稱：FTCD兔多克隆抗體
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貨號：CSB-PA009029ESR2HU
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規格：￥440
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圖片：
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Western blot
All lanes: FTCD antibody at 5.46μg/ml
Lane 1: HepG2 whole cell lysate
Lane 2: 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 59, 62, 53, 17 kDa
Observed band size: 59 kDa -
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA009029ESR2HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA009029ESR2HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) FTCD Polyclonal antibody
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Uniprot No.：
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基因名：FTCD
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別名：Formimidoyltetrahydrofolate cyclodeaminase antibody; Formimidoyltransferase cyclodeaminase antibody; Formiminotetrahydrofolate cyclodeaminase antibody; Formiminotransferase cyclodeaminase antibody; Formiminotransferase-cyclodeaminase antibody; FTCD antibody; FTCD_HUMAN antibody; Glutamate formiminotransferase antibody; Glutamate formyltransferase antibody; LCHC 1 antibody; LCHC1 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Formimidoyltransferase-cyclodeaminase protein (412-541AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, WB, IHC
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推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool.; Binds and promotes bundling of vimentin filaments originating from the Golgi.
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基因功能參考文獻：
- The formiminotransferase-cyclodeaminase allelic spectrum comprised of 12 distinct variants including 5 missense alterations, an in-frame deletion, two frameshift variants and four nonsense variants with the remaining alterations predicted to affect mRNA processing/stability. PMID: 29178637
- FTCD is a positive regulator of the hypoxia-HIF signaling pathway and has an important role in cell proliferation, metabolism and migration in HepG2 cells PMID: 24686083
- The FTCD promoter is activated by serum depletion according to promoter reporter assays in HEK 293 cells. PMID: 20494980
- Scyl1 interacts with 58K/formiminotransferase cyclodeaminase (FTCD) and golgin p115, and is required for the maintenance of Golgi morphology PMID: 20209057
- Disease-causing mutations have been identified in the FTCD gene in three patients with the putative autosomal recessive disorder glutamate formiminotransferase deficiency. PMID: 12815595
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相關疾病：Glutamate formiminotransferase deficiency (FIGLU-URIA)
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亞細胞定位：Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Golgi apparatus. Note=More abundantly located around the mother centriole.
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蛋白家族：Cyclodeaminase/cyclohydrolase family; Formiminotransferase family
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數據庫鏈接：
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