FLRT3 Antibody

中文名稱：

FLRT3兔多克隆抗體
貨號：

CSB-PA882162LA01HU
規格：

￥440
圖片：
Western blot
All lanes: DARS2 antibody at 16μg/ml
Lane 1: Mouse heart tissue
Lane 2: Mouse liver tissue
Lane 3: Mouse brain tissue
Lane 4: Mouse skeletal muscle tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 73 kDa
Observed band size: 73 kDa

Immunofluorescent analysis of HepG2 cells using CSB-PA882162LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品描述：

The FLRT3 antibody is a high-quality polyclonal antibody suitable for the detection of the FLRT3 protein from human and mouse samples. It is available as the unconjugated IgG isoform. This FLRT3 antibody is raised in the rabbit against a partial recombinant protein mapping within amino acids 209-264 of human FLRT3. This FLRT3 antibody is purified by protein G affinity chromatography with a purity of up to 95%. And it has been validated for use in ELISA, WB, and IF applications.

Its target protein FLRT3 plays important roles in various cellular processes such as axon guidance, cell migration, and synapse formation during development. FLRT3 is predominantly expressed in the nervous system and is involved in the formation and maintenance of neural circuits.
產品名稱：

Rabbit anti-Homo sapiens (Human) FLRT3 Polyclonal antibody
Uniprot No.：

Q9NZU0
基因名：

FLRT3
別名：

fibronectin leucine rich transmembrane protein 3 antibody; Fibronectin-like domain-containing leucine-rich transmembrane protein 3 antibody; FLRT 3 antibody; FLRT3 antibody; FLRT3_HUMAN antibody; KIAA1469 antibody; Leucine-rich repeat transmembrane protein FLRT3 antibody
宿主：

Rabbit
反應種屬：

Human, Mouse
免疫原：

Recombinant Human Leucine-rich repeat transmembrane protein FLRT3 protein (209-264AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，FLRT3 Antibody (CSB-PA882162LA01HU)，的標記方式是Non-conjugated。對于FLRT3 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA882162LB01HU	FLRT3 Antibody, HRP conjugated	ELISA
FITC	CSB-PA882162LC01HU	FLRT3 Antibody, FITC conjugated
Biotin	CSB-PA882162LD01HU	FLRT3 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB, IF

推薦稀釋比：

Application	Recommended Dilution
WB	1:1000-1:5000
IF	1:50-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Functions in cell-cell adhesion, cell migration and axon guidance, exerting an attractive or repulsive role depending on its interaction partners. Plays a role in the spatial organization of brain neurons. Plays a role in vascular development in the retina. Plays a role in cell-cell adhesion via its interaction with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells. Interaction with the intracellular domain of ROBO1 mediates axon attraction towards cells expressing NTN1. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5B, and possibly also other UNC-5 family members. Promotes neurite outgrowth (in vitro). Mediates cell-cell contacts that promote an increase both in neurite number and in neurite length. Plays a role in the regulation of the density of glutamaergic synapses. Plays a role in fibroblast growth factor-mediated signaling cascades. Required for normal morphogenesis during embryonic development, but not for normal embryonic patterning. Required for normal ventral closure, headfold fusion and definitive endoderm migration during embryonic development. Required for the formation of a normal basement membrane and the maintenance of a normal anterior visceral endoderm during embryonic development.
基因功能參考文獻：
1. Low FLRT3 expression is associated with lung graft dysfunction. PMID: 27421969
相關疾病：

Hypogonadotropic hypogonadism 21 with or without anosmia (HH21)
亞細胞定位：

Cell membrane; Single-pass membrane protein. Endoplasmic reticulum membrane. Cell junction, focal adhesion. Secreted. Cell projection, axon. Cell projection, growth cone membrane.
組織特異性：

Expressed in kidney, brain, pancreas, skeletal muscle, lung, liver, placenta, and heart.
數據庫鏈接：

HGNC: 3762

OMIM: 604808

KEGG: hsa:23767

STRING: 9606.ENSP00000339912

UniGene: Hs.41296

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