FGFR1OP2 Antibody

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) FGFR1OP2 Polyclonal antibody
Uniprot No.：

Q9NVK5
基因名：

FGFR1OP2
別名：

DKFZp564O1863 antibody; FGFR1 oncogene partner 2 antibody; FGFR1OP2 antibody; FGOP2_HUMAN antibody; Fibroblast growth factor receptor 1 oncogene partner 2 antibody; HSPC123 antibody; HSPC123 like antibody; WIT3.0 antibody; Wound inducible transcript 3.0 antibody
宿主：

Rabbit
反應種屬：

Human, Mouse
免疫原：

Recombinant Human FGFR1 oncogene partner 2 protein (1-172AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，FGFR1OP2 Antibody (CSB-PA008644LA01HU)，的標記方式是Non-conjugated。對于FGFR1OP2 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA008644LB01HU	FGFR1OP2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA008644LC01HU	FGFR1OP2 Antibody, FITC conjugated
Biotin	CSB-PA008644LD01HU	FGFR1OP2 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB

推薦稀釋比：

Application	Recommended Dilution
WB	1:1000-1:5000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May be involved in wound healing pathway.
基因功能參考文獻：
1. The patient with minor allele of ss518063493 may be associated with excessive atrophy of edentulous mandible whereas the patients with that of rs840869 are not associated in Korean population. PMID: 22880093
2. patients with the minor allele of rs840869 or rs859024 of FGFR1OP2 were associated with excessive atrophy of edentulous mandible PMID: 21283824
3. FGFR1OP2/wit3.0 may regulate cell motility and stimulate wound closure. PMID: 19959814
4. FGFR1OP2 is a new FGFR1 fusion gene involving a chromosomes 12X8 translocation in a 8p11 myeloproliferative syndrome patient. PMID: 15034873
相關疾病：

A chromosomal aberration involving FGFR1OP2 may be a cause of stem cell myeloproliferative disorder (MPD). Insertion ins(12;8)(p11;p11p22) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T-cell or B-cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion protein FGFR1OP2-FGFR1 may exhibit constitutive kinase activity and be responsible for the transforming activity.
亞細胞定位：

Cytoplasm.
蛋白家族：

SIKE family
組織特異性：

Expressed in bone marrow, spleen and thymus.
數據庫鏈接：

HGNC: 23098

OMIM: 608858

KEGG: hsa:26127

STRING: 9606.ENSP00000229395

UniGene: Hs.591162

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