FGF16 Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

O43320
基因名：

FGF16
別名：

FGF 16 antibody; FGF-16 antibody; Fgf16 antibody; FGF16_HUMAN antibody; Fibroblast growth factor 16 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Synthesized peptide derived from the Internal region of Human FGF-16.
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

WB, ELISA

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:20000

Protocols：

Western Blotting (WB) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation, and is required for normal cardiomyocyte proliferation and heart development.
基因功能參考文獻(xiàn)：
1. Experiments demonstrated FGF16 could promote proliferation of NCL-H460 cells by activating Akt, Erk1/2, and p38 MAPK signaling, whereas JNK had no significant effect. PMID: 28409700
2. Identification of an FGF16 mutation in metacarpal 4-5 fusion. PMID: 24878828
3. impaired FGF16 function may also be responsible for connective tissue symptoms in MF4 patients. PMID: 24706454
4. Fgf-16 gene is a target for NF-kappaB activation in the postnatal heart. PMID: 20097674
5. HUVEC clearly demonstrated chemotaxis towards FGF16. FGF16 enhanced cell migration in response to mechanical damage & failed to induce endothelial cell proliferation or sprouting in a three-dimensional in vitro angiogenesis assay. PMID: 16756958
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相關(guān)疾病：

Metacarpal 4-5 fusion (MF4)
亞細(xì)胞定位：

Secreted.
蛋白家族：

Heparin-binding growth factors family
數(shù)據(jù)庫鏈接：

HGNC: 3672

OMIM: 300827

KEGG: hsa:8823

STRING: 9606.ENSP00000399324

UniGene: Hs.666364

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