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FBXO44 Antibody, FITC conjugated

說明書

中文名稱：

FBXO44兔多克隆抗體, FITC偶聯(lián)
貨號：

CSB-PA872497LC01HU
規(guī)格：

￥880
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) FBXO44 Polyclonal antibody
Uniprot No.：

Q9H4M3
基因名：

FBXO44
別名：

5730411K09 antibody; AV001623 antibody; DKFZp781J0852 antibody; F box gene 3 antibody; F box only protein 44 antibody; F box only protein 6a antibody; F box protein 44 antibody; F box protein FBX30 antibody; F box/G domain protein 3 antibody; F-box only protein 44 antibody; F-box protein FBX30 antibody; F-box/G-domain protein 3 antibody; FBG3 antibody; FBX30 antibody; FBX44 antibody; FBX44_HUMAN antibody; FBX6A antibody; Fbxo44 antibody; Fbxo6a antibody; MGC14140 antibody; RGD1562463 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human F-box only protein 44 protein (1-224AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

FITC
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
基因功能參考文獻：
1. Although the overall structure of FBG3 is similar to that of Fbs1, the residues that form the Fbs1 carbohydrate-binding pocket failed to be superposed with the corresponding residues of FBG3. PMID: 26460611
2. FBXO44-mediated degradation of RGS2 protein uniquely depends on a Cul4B/DDB1 complex. PMID: 25970626
3. FBXO44 mediates BRCA1 ubiquitination and degradation PMID: 23086937
4. Skp1 and Fbg3 were co-expressed in E. coli. The plate-shaped crystals belonged to space group P2(1)2(1)2(1), with unit-cell parameters a = 34.1, b = 76.6, c = 193.9 A and one molecule per asymmetric unit. PMID: 20057081
組織特異性：

Abundantly expressed in brain and kidney. Expressed at lower levels in heart, spleen and liver.
數據庫鏈接：

HGNC: 24847

OMIM: 609111

KEGG: hsa:93611

STRING: 9606.ENSP00000251547

UniGene: Hs.556006

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