FBP2 Antibody

中文名稱：

FBP2兔多克隆抗體
貨號(hào)：

CSB-PA089265
規(guī)格：

￥1100
圖片：
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA089265(FBP2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA089265(FBP2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
其他：

產(chǎn)品詳情

Uniprot No.：

O00757
基因名：

FBP2
別名：

6-bisphosphatase isozyme 2 antibody; 6-bisphosphate 1-phosphohydrolase 2 antibody; D fructose 1 6 bisphosphate 1 phosphohydrolase 2 antibody; D-fructose-1 antibody; F16P2_HUMAN antibody; FBP 2 antibody; fbp2 antibody; FBPase 2 antibody; FBPase antibody; fructose 1 6 bisphosphatase 2 antibody; Fructose 1 6 bisphosphatase isozyme 2 antibody; Fructose-1 antibody; Hexosediphosphatase antibody; MGC142192 antibody; Muscle FBPase antibody; Muscle fructose bisphosphatase antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Fusion protein of Human FBP2
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

Antigen affinity purification
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,IHC

推薦稀釋比：

Application	Recommended Dilution
ELISA	1:2000-1:5000
IHC	1:50-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate.
基因功能參考文獻(xiàn)：
1. Results demonstrate that truncation of the evolutionarily conserved N-terminal residues of FBP2 results in a loss of its mitochondria-protective functions. PMID: 24412565
2. FBP2 does negatively regulate cell growth, and reduced expression of FBP2 may contribute to carcinogenesis for gastric cancer. PMID: 24063558
3. The key role in strong AMP binding to muscle isozyme play K20, T177 and Q179. PMID: 16213487
4. The existence of highly AMP-sensitive muscle-like FBPase, activity of which is regulated by metabolite-dependent interaction with aldolase enables the precise regulation of muscle energy expenditures. PMID: 18214967
亞細(xì)胞定位：

Cell junction. Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere, Z line.
蛋白家族：

FBPase class 1 family
組織特異性：

Expressed in skeletal muscle (at protein level).
數(shù)據(jù)庫(kù)鏈接：

HGNC: 3607

OMIM: 603027

KEGG: hsa:8789

STRING: 9606.ENSP00000364486

UniGene: Hs.61255

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