FARP2 Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

O94887
基因名：

FARP2
別名：

FARP2 antibody; FARP2_HUMAN antibody; FERM antibody; FERM domain including RhoGEF antibody; FERM; RhoGEF and pleckstrin domain protein 2 antibody; FERM; RhoGEF and pleckstrin domain-containing protein 2 antibody; FGD1 related Cdc42 GEF antibody; FIR antibody; FRG antibody; KIAA0793 antibody; PH domain-containing family C member 3 antibody; Pleckstrin homology domain-containing family C member 3 antibody; PLEKHC3 antibody; RhoGEF and pleckstrin domain protein 2 antibody; RhoGEF and pleckstrin domain-containing protein 2 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse
免疫原：

Synthesized peptide derived from the Internal region of Human FIR.
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

WB, IF, ELISA

推薦稀釋比：

Protocols：

Western Blotting (WB) Protocol
Immunofluorescence (IF) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion.
基因功能參考文獻(xiàn)：
1. FRG is a member of Cdc42-GEF and plays an important role in the signaling pathway downstream of G protein-coupled receptors PMID: 12771149
數(shù)據(jù)庫鏈接：

HGNC: 16460

OMIM: 617586

KEGG: hsa:9855

STRING: 9606.ENSP00000264042

UniGene: Hs.726316

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