EXOG Antibody

說明書

中文名稱：

EXOG兔多克隆抗體
貨號：

CSB-PA007666ESR2HU
規(guī)格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA007666ESR2HU at dilution of 1:100
其他：

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) EXOG Polyclonal antibody
Uniprot No.：

Q9Y2C4
基因名：

EXOG
別名：

Endo G like 1 antibody; Endo G-like 1 antibody; Endo/exonuclease (5'-3'); endonuclease G like antibody; ENDOGL 1 antibody; ENDOGL1 antibody; ENDOGL2 antibody; Endonuclease G like 1 antibody; Endonuclease G like 2 antibody; Endonuclease G-like 1 antibody; ENGL a antibody; ENGL antibody; ENGL B antibody; ENGLA antibody; ENGLB antibody; Exog antibody; EXOG_HUMAN antibody; MGC125944 antibody; MGC125945 antibody; mitochondrial antibody; Nuclease EXOG antibody; Nuclease EXOG mitochondrial antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Nuclease EXOG, mitochondrial protein (144-368AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
產(chǎn)品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single-stranded DNA and 5'-3' exonuclease activity.
基因功能參考文獻：
1. Data suggest a role of exo/endonuclease G nuclease (hEXOG) in pathway for mitochondrial DNA repair. PMID: 28466855
2. These data indicate that HSV-1 UL12.5 deploys cellular proteins, including ENDOG and EXOG, to destroy mtDNA and contribute to a growing body of literature highlighting roles for ENDOG and EXOG in mtDNA maintenance. PMID: 23986585
3. EXOG depletion induces persistent SSBs in the mtDNA, enhances ROS levels, and causes apoptosis in normal cells but not in mt genome-deficient rho0 cells. PMID: 21768646
4. ENDOGL1 is a candidate disease-susceptibility gene for type 2 diabetes in a Japanese population PMID: 17415550
5. Human endonuclease G-like-1 is a dimeric mitochondrial enzyme that displays 5'-3' exonuclease activity and further differs from EndoG in substrate specificity PMID: 18187503
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亞細胞定位：

Mitochondrion inner membrane.
蛋白家族：

DNA/RNA non-specific endonuclease family
組織特異性：

Ubiquitous.
數(shù)據(jù)庫鏈接：

HGNC: 3347

OMIM: 604051

KEGG: hsa:9941

STRING: 9606.ENSP00000287675

UniGene: Hs.517897

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