EXOC4 Antibody
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中文名稱：EXOC4兔多克隆抗體
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貨號：CSB-PA007882GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：EXOC4
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別名：dSec8 antibody; EXOC 4 antibody; Exoc4 antibody; EXOC4_HUMAN antibody; Exocyst complex component 4 antibody; Exocyst complex component SEC8 antibody; KIAA1699 antibody; MGC27170 antibody; REC 8 antibody; REC8 antibody; rSec 8 antibody; Sec 8 antibody; Sec 8p antibody; Sec8 antibody; SEC8 like 1 antibody; SEC8 protein antibody; Sec8L1 antibody; Sec8p antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human EXOC4
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
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基因功能參考文獻：
- Sec8 regulates N-cadherin expression by controlling Smad3 and Smad4 expression through CBP, thereby mediating the epithelial-mesenchymal transition. PMID: 27769780
- Sec8 regulate Bcl-2 and Mcl-1 expressions but not Bcl-xl in malignant peripheral nerve sheath tumor cells. PMID: 26892009
- Sec8 regulates histone-modifying proteins ATF2 and RNF20. PMID: 26283729
- Sec8 knockdown in HSC3 cells resulted in reduced expressions of PAK1 and PAK2 by upregulating Pirh2 and Siah1 expression, which inhibited the ERK or p38 MAPK signalling pathway and cytokeratin8 phosphorylation and cell migration. PMID: 25725287
- knockdown of Sec8 enhances the binding of JIP4 to MAPK kinase 4, thereby decreasing the phosphorylation of MAPK kinase 4, JNK, and p38. PMID: 25244576
- Exome sequencing revealed a likely pathogenic mutation in three novel candidate MKS disease genes-C5orf42, EVC2 and SEC8 (also known as EXOC4), which encodes an exocyst protein with an established role in ciliogenesis PMID: 23169490
- High Sec8 expression is associated with progression of oral squamous-cell carcinoma by secretion of matrix metalloproteinases. PMID: 23207790
- EXOC4 is involved in insulin-stimulated glucose transport and may be a candidate for an association with type 2 diabetes. PMID: 18498660
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亞細胞定位：Midbody, Midbody ring. Cell projection.
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蛋白家族：SEC8 family
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數據庫鏈接：
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