EXOC3 Antibody, Biotin conjugated
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中文名稱：EXOC3兔多克隆抗體, Biotin偶聯(lián)
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貨號：CSB-PA527663LD01HU
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) EXOC3 Polyclonal antibody
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Uniprot No.：
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基因名：EXOC3
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別名：EXOC 3 antibody; Exoc3 antibody; EXOC3_HUMAN antibody; Exocyst complex component 3 antibody; Exocyst complex component Sec 6 antibody; Exocyst complex component Sec6 antibody; rSec 6 antibody; Sec 6 antibody; Sec 6 homolog antibody; Sec 6p antibody; Sec6 antibody; SEC6 L1 antibody; SEC6 like 1 antibody; Sec6 protein antibody; SEC6L1 antibody; Sec6p antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human Exocyst complex component 3 protein (410-756AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Antigen Affinity purified & Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點(diǎn)詳情
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功能：Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
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基因功能參考文獻(xiàn)：
- Sec6 regulate Bcl-2 and Mcl-1 expressions but not Bcl-xl in malignant peripheral nerve sheath tumor cells. PMID: 26892009
- Sec6 regulates NF-kappaB transcriptional activity via the control of the phosphorylation of IkappaBalpha, p90RSK1, and ERK PMID: 26247921
- The study explores the role of the exocyst complex component Sec6/8 in genomic stability. PMID: 26283729
- Sec6 regulates cytoplasmic translocation of p27 through p27 phosphorylation at Thr157, thereby promoting p27 degradation in the cytoplasm via interaction with Jab1 and Siah1 and suppressing cell cycle progression. PMID: 24949832
- Data demonstrate that the expression of alpha-E-catenin is increased by Sec6 siRNAs, and E-cadherin and beta-catenin localize mainly at the cell-cell contact region in HSC3 cells, which were transfected with Sec6 siRNA. PMID: 22381337
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亞細(xì)胞定位：Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone. Midbody. Golgi apparatus. Cell projection, neuron projection.
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蛋白家族：SEC6 family
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組織特異性：Expressed in epididymis (at protein level).
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數(shù)據(jù)庫鏈接：
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