ERGIC1 Antibody

說明書

產品詳情

Uniprot No.：

Q969X5
基因名：

ERGIC1
別名：

ERGIC1; ERGIC32; KIAA1181; HT034; Endoplasmic reticulum-Golgi intermediate compartment protein 1; ER-Golgi intermediate compartment 32 kDa protein; ERGIC-32
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human ERGIC1
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Possible role in transport between endoplasmic reticulum and Golgi.
基因功能參考文獻：
1. Homozygous pathogenic variant in the endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 protein (ERGIC1) gene was identified in arthrogryposis multiplex congenita (AMC) neuropathic type. PMID: 28317099
2. ERGIC1 might play an inhibitory role in the initiation and progression of gastric cancer. PMID: 29549924
3. Data indicate that abnormal ERGIC1 and DNA-PKcs expression may play an important role in gastric cancer initiation. PMID: 28970727
4. AIM1, ERGIC1, and TPX2 were shown to be highly expressed especially in prostate cancer tissues, and high mRNA expression of ERGIC1 and TMED3 associated with AR and ERG oncogene expression PMID: 22761906
5. ERGIC-32 functions as a modulator of the hErv41-hErv46 complex by stabilizing hErv46 PMID: 15308636
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亞細胞定位：

Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Cycles between the endoplasmic reticulum and the Golgi.
蛋白家族：

ERGIC family
數據庫鏈接：

HGNC: 29205

KEGG: hsa:57222

STRING: 9606.ENSP00000377374

UniGene: Hs.509163

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