EMR1 Antibody

說明書

產品詳情

Uniprot No.：

Q14246
基因名：

ADGRE1
別名：

ADGRE1 antibody; Adhesion G protein coupled receptor E1 antibody; Adhesion G protein-coupled receptor E1 antibody; AGRE1_HUMAN antibody; Cell surface glycoprotein EMR1 antibody; Cell surface glycoprotein F4/80 antibody; DD7A5 7 antibody; Egf like module containing mucin like hormone receptor like 1 antibody; Egf like module containing mucin like hormone receptor like sequence 1 antibody; EGF like module receptor 1 antibody; EGF TM7 antibody; EGF-like module receptor 1 antibody; EGF-like module-containing mucin-like hormone receptor-like 1 antibody; EGFTM7 antibody; EMR 1 antibody; EMR1 antibody; EMR1 hormone receptor antibody; Gpf480 antibody; Ly71 antibody; Lymphocyte antigen 71 antibody; TM7LN3 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Synthesized peptide derived from the C-terminal region of Human EMR1.
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產品提供形式：

Liquid
應用范圍：

WB, ELISA

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:5000

Protocols：

Western Blotting (WB) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development.
基因功能參考文獻：
1. EMR1 expression is significantly upregulated in human masticatory mucosa during wound healing PMID: 28005267
2. Additional transcription changes likely associated with Th2-like eosinophilic inflammation were prominent and included increased EMR1&3. PMID: 20625511
3. Highly specific marker for eosinophils. PMID: 17823986
亞細胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
組織特異性：

Expression is restricted to eosinophils.
數據庫鏈接：

HGNC: 3336

OMIM: 600493

KEGG: hsa:2015

STRING: 9606.ENSP00000311545

UniGene: Hs.2375

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