EME1 Antibody

中文名稱：

EME1兔多克隆抗體
貨號：

CSB-PA856897LA01HU
規(guī)格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA856897LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA856897LA01HU at dilution of 1:100
其他：

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) EME1 Polyclonal antibody
Uniprot No.：

Q96AY2
基因名：

EME1
別名：

6820428D13 antibody; Crossover junction endonuclease EME1 antibody; EC 3.1.22.- antibody; EME1 antibody; Eme1 essential meiotic endonuclease 1 homolog 1 (S. pombe) antibody; EME1; S. pombe; homolog of; 1 antibody; EME1_HUMAN antibody; essential meiotic endonuclease 1 homolog 1 (S pombe) antibody; Essential Meiotic Endonuclease 1 Homolog 1 antibody; essential meiotic endonuclease 1 homolog 2 antibody; Essential meiotic endonuclease 1; S. pombe; homolog of; 1 antibody; FLJ31364 antibody; hMMS4 antibody; homolog of yeast EME1 endonuclease antibody; MGC106543 antibody; MMS4 antibody; MMS4 homolog antibody; MMS4L antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Crossover junction endonuclease EME1 protein (1-583AA)
免疫原種屬：

Homo sapiens (Human)

標(biāo)記方式：

Non-conjugated

本頁面中的產(chǎn)品，EME1 Antibody (CSB-PA856897LA01HU)，的標(biāo)記方式是Non-conjugated。對于EME1 Antibody，我們還提供其他標(biāo)記。見下表：

標(biāo)記方式	貨號	產(chǎn)品名稱	應(yīng)用
HRP	CSB-PA856897LB01HU	EME1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA856897LC01HU	EME1 Antibody, FITC conjugated
Biotin	CSB-PA856897LD01HU	EME1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.
基因功能參考文獻(xiàn)：
1. The data suggest that subnuclear relocalization is relevant for the function of Mus81-Mms4 complex in response to DNA damage and, probably, of the endonucleases that colocalize with it. PMID: 28813668
2. EME-1 deficiency affects cell cycle progression and promotes DNA rereplication. PMID: 16456034
3. Low Eme1 levels were more sensitive to the drug than tumors with high levels. PMID: 19267403
亞細(xì)胞定位：

Nucleus, nucleolus. Note=Recruited to regions of DNA damage in S-phase cells.
蛋白家族：

EME1/MMS4 family
數(shù)據(jù)庫鏈接：

HGNC: 24965

OMIM: 610885

KEGG: hsa:146956

STRING: 9606.ENSP00000376952

UniGene: Hs.514330

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