ELOVL2 Antibody, FITC conjugated
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中文名稱：ELOVL2兔多克隆抗體, FITC偶聯
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貨號：CSB-PA889139LC01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) ELOVL2 Polyclonal antibody
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Uniprot No.：
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基因名：ELOVL2
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別名：ELOVL2; ELG3; SSC2; Elongation of very long chain fatty acids protein 2; 3-keto acyl-CoA synthase ELOVL2; ELOVL fatty acid elongase 2; ELOVL FA elongase 2; Very long chain 3-ketoacyl-CoA synthase 2; Very long chain 3-oxoacyl-CoA synthase 2
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Elongation of very long chain fatty acids protein 2 protein (91-174AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
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靶點詳情
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功能：Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA), acting specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. May participate in the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
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基因功能參考文獻：
- Results shows that ELOVL2 promoter displays an exceptionally consistent increase in DNA methylation with age in all tissues. PMID: 29848354
- ELOVL2 methylation is a marker of cell divisions occurring during human aging PMID: 27672102
- common variations not associated with polyunsaturated fatty acid levels in breast milk PMID: 28245901
- Estrogen Enhances the Expression of the Polyunsaturated Fatty Acid Elongase Elovl2 via ERalpha in Breast Cancer Cells PMID: 27788154
- Polymorphisms in the ELOVL2 gene were not associated with the risk of developing allergic disease PMID: 26633493
- results show that the ELOVL2 locus provides a very good source of information about human chronological age based on analysis of blood, including bloodstains, and it may constitute a powerful and reliable predictor in future forensic age estimation models PMID: 25450787
- we do not found the association between rs3756593 of ELOVL2 gene and acute coronary syndrome in Chinese Han population PMID: 23555103
- Methylation of ELOVL2 gene is a new epigenetic marker of age. PMID: 23061750
- rs3756963 in ELOVL2 gene may be associated with paranoid schizophrenia. PMID: 21560298
- gene interaction analysis showed that the combined genotype of FADS1 rs174556 (T/T) and ELOVL2 rs3756963 (T/T) was weakly associated with coronary artery disease PMID: 21917437
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亞細胞定位：Endoplasmic reticulum membrane; Multi-pass membrane protein.
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蛋白家族：ELO family, ELOVL2 subfamily
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組織特異性：Liver and testis.
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數據庫鏈接：
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