Delta-ctenitoxin-Pn1a Antibody

產品詳情

產品名稱：

Rabbit anti-Phoneutria nigriventer N/A Polyclonal antibody
Uniprot No.：

P59368
基因名：

N/A
別名：

antibody; Delta-ctenitoxin-Pn1a antibody; Delta-CNTX-Pn1a antibody; Insecticidal neurotoxin Tx4(6-1) antibody; PnTx4(6-1) antibody
宿主：

Rabbit
反應種屬：

Phoneutria nigriventer
免疫原：

Recombinant Phoneutria nigriventer Delta-ctenitoxin-Pn1a protein (35-82AA)
免疫原種屬：

Phoneutria nigriventer

標記方式：

Non-conjugated

本頁面中的產品，Delta-ctenitoxin-Pn1a Antibody (CSB-PA349440HA01EUV)，的標記方式是Non-conjugated。對于Delta-ctenitoxin-Pn1a Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA349440HB01EUV	Delta-ctenitoxin-Pn1a Antibody, HRP conjugated	ELISA
FITC	CSB-PA349440HC01EUV	Delta-ctenitoxin-Pn1a Antibody, FITC conjugated
Biotin	CSB-PA349440HD01EUV	Delta-ctenitoxin-Pn1a Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

This neurotoxin binds at site 3 of insect voltage-activated sodium channels (Nav) and prolongs evoked axonal action potentials by a slowing down of sodium current inactivation. The toxin also inhibits glutamate uptake from rat brain synaptosomes. It reversibly inhibits the N-methyl-D-aspartate (NMDA)-subtype of ionotropic glutamate receptor (GRIN). In addition, the toxin shows antinociceptive effect in all rat pain models tested (inflammatory, neuropathic and nociceptive). The antinociceptive effect is partially blocked when selective antagonists of both mu- and delta-opioid receptors are administered, revealing that the antinociceptive effect of the toxin involves both opiod and cannabinoid endogenous systems. In vivo, it is highly toxic to house fly (Musca domestica), toxic to cockroach, but has no effect when intracerebroventricularly injected into mice.
亞細胞定位：

Secreted.
蛋白家族：

Spider toxin Tx2 family
組織特異性：

Expressed by the venom gland.

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