DUSP8 Antibody

說明書

中文名稱：

DUSP8兔多克隆抗體
貨號：

CSB-PA132342
規(guī)格：

￥1100
圖片：
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA132342(DUSP8 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
其他：

產(chǎn)品詳情

Uniprot No.：

Q13202
基因名：

DUSP8
別名：

C11orf81 antibody; Chromosome 11 open reading frame 81 antibody; Deubiquitinating enzyme 8 antibody; Dual Specificity Phosphatase 8 antibody; Dual specificity phosphatase M3/6 antibody; Dual specificity protein phosphatase 8 antibody; Dual specificity protein phosphatase hVH 5 antibody; Dual specificity protein phosphatase hVH-5 antibody; DUS8 antibody; DUS8_HUMAN antibody; DUSP8 antibody; EC 3.1.3.16 antibody; EC 3.1.3.48 antibody; FLJ42476 antibody; FLJ42958 antibody; H1 phosphatase vaccinia virus homolog antibody; H1 phosphatase; vaccinia virus; homolog of antibody; HB5 antibody; hUBPy antibody; HVH5 antibody; HVH8 antibody; M3/6; mouse; homolog of antibody; Neuronal tyrosine threonine phosphatase 1 antibody; Serine/threonine specific protein phosphatase antibody; Ubiquitin carboxyl terminal hydrolase 8 antibody; Ubiquitin specific processing protease 8 antibody; Ubiquitin thiolesterase 8 antibody; VH5 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse
免疫原：

Synthetic peptide of Human DUSP8
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

Antigen affinity purification
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
產(chǎn)品提供形式：

Liquid
應用范圍：

ELISA,IHC

推薦稀釋比：

Application	Recommended Dilution
ELISA	1:2000-1:10000
IHC	1:50-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Has phosphatase activity with synthetic phosphatase substrates and negatively regulates mitogen-activated protein kinase activity, presumably by catalysing their dephosphorylation. Expected to display protein phosphatase activity toward phosphotyrosine, phosphoserine and phosphothreonine residues.
基因功能參考文獻：
1. The phosphorylation of the M3/6 phosphatase by JNK in response to stress stimuli results in attenuation of phosphatase activity and acceleration of JNK activation. PMID: 22100391
2. DUSP8 is genetically linked to alcohol dependence and was found on chromosome 11p15.5 PMID: 13129832
3. Because this variant of hVH-5 lacked intronic sequences in its genomic structure, we suggest it might be a processed pseudogene of hVH-5. PMID: 15899389
亞細胞定位：

Cytoplasm. Nucleus.
蛋白家族：

Protein-tyrosine phosphatase family, Non-receptor class dual specificity subfamily
組織特異性：

Abundant in brain, heart and skeletal muscle.
數(shù)據(jù)庫鏈接：

HGNC: 3074

OMIM: 602038

KEGG: hsa:1850

STRING: 9606.ENSP00000329539

UniGene: Hs.41688

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