DSTN Antibody
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中文名稱：DSTN兔多克隆抗體
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貨號：CSB-PA671890
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規(guī)格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA671890(DSTN Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200) -
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA671890(DSTN Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：DSTN
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別名：2610043P17Rik antibody; ACTDP antibody; Actin depolymerizing factor antibody; Actin-depolymerizing factor antibody; ADF antibody; AU042046 antibody; bA462D18.2 antibody; corn1 antibody; DEST_HUMAN antibody; Destrin (actin depolymerizing factor) antibody; Destrin antibody; DSN antibody; Dstn antibody; Epididymis luminal protein 32 antibody; HEL32 antibody; Sid 23 antibody; sid23p antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Fusion protein of Human DSTN
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:2000-1:5000 IHC 1:25-1:100 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情
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功能：Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers (G-actin). Acts in a pH-independent manner.
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基因功能參考文獻：
- analysis of human Cof1, Cof2, and ADF effects on actin filament severing and turnover PMID: 26996939
- Destrin is upregulated in nerve-invasive pancreatic cancer cells and its expression might be related to perineural invasiveness PMID: 22898637
- The ADF/cofilin1-dependent severing of actin filaments exposes and promotes the activation of SPCA1, which pumps Ca(2+) into the lumen of the TGN for the sorting of the class of secretory cargo that binds Ca(2+). PMID: 21571222
- Changes in the expression of cytoskeletal regulatory proteins such as LIMK and cofilin may play a role in weakening thoracic aortic medial tissue, as a precondition to thoracic aortic dissection. PMID: 20873970
- The results of this study suggested that temporally regulated ADF/cofilin activities function in postsynaptic modifications of receptor number and spine size during synaptic plasticity. PMID: 20835250
- differences in actin binding by human ADF and cofilin PMID: 11812157
- Important sequence differences between actin-depolymerizing factor/cofilin were correlated with unique structural determinants in the F-actin-binding site to account for differences in biochemical activities of the two proteins. PMID: 14627701
- downregulated following UV exposure in epidermis PMID: 15816841
- In the absence of any crystal structures of ADF or cofilin in complex with actin, these studies provide further information about the binding sites on F-actin for these important actin regulatory proteins. PMID: 17196218
- destrin is a significant regulator of various processes important for invasive phenotype of human colon cancer Isreco1 cells whereas cofilin-1 may be involved in only a subset of them PMID: 17583572
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蛋白家族：Actin-binding proteins ADF family
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組織特異性：Widely distributed in various tissues.
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數(shù)據(jù)庫鏈接：
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