DSE Antibody, HRP conjugated
-
中文名稱：DSE兔多克隆抗體, HRP偶聯(lián)
-
貨號(hào)：CSB-PA890925LB01HU
-
規(guī)格：￥880
-
其他：
產(chǎn)品詳情
-
產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) DSE Polyclonal antibody
-
Uniprot No.：
-
基因名：
-
別名：Chondroitin glucuronate 5 epimerase antibody; Chondroitin-glucuronate 5-epimerase antibody; Dermatan sulfate epimerase antibody; Dermatan-sulfate epimerase antibody; DS epimerase antibody; DSE antibody; DSE_HUMAN antibody; DSEPI antibody; OTTHUMP00000040406 antibody; SART 2 antibody; SART-2 antibody; Squamous cell carcinoma antigen recognized by T cells 2 antibody; Squamous cell carcinoma antigen recognized by T-cells 2 antibody
-
宿主：Rabbit
-
反應(yīng)種屬：Human
-
免疫原：Recombinant Human Dermatan-sulfate epimerase protein (23-270AA)
-
免疫原種屬：Homo sapiens (Human)
-
標(biāo)記方式：HRP
-
克隆類型：Polyclonal
-
抗體亞型：IgG
-
純化方式：>95%, Protein G purified
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式：Liquid
-
應(yīng)用范圍：ELISA
-
Protocols：
-
儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
-
功能：Converts D-glucuronic acid to L-iduronic acid (IdoUA) residues. Plays an important role in the biosynthesis of the glycosaminoglycan/mucopolysaccharide dermatan sulfate.
-
基因功能參考文獻(xiàn)：
- Study showed that DSE is frequently upregulated in human glioma tissue and cell lines and associated with a worse tumor grade and poor overall survival. Its knockdown suppresses malignant phenotypes, whereas DSE overexpression enhances glioma cell malignancy, both in vitro and in vivo. Mechanically, DSE modulates HB-EGF-induced EGFR/ErbB2 activity and downstream signaling. PMID: 29864158
- study identified a homozygous DSE missense mutation (c.803C>T, p.S268L) in a male child with musculocontractural type of Ehlers-Danlos syndrome; data indicate mutation affects the epimerase activity, resulting in reduced dermatan sulfate (DS) biosynthesis and an increased synthesis or an accumulation or reduced conversion of chondroitin sulfate PMID: 23704329
- Dermatan sulfate epimerase 1 was highly upregulated in esophagus squamous cell carcinoma PMID: 22350411
- Identification of the active site of DS-epimerase 1 and requirement of N-glycosylation for enzyme function. PMID: 19004833
-
相關(guān)疾?。?/div>Ehlers-Danlos syndrome, musculocontractural type 2 (EDSMC2)亞細(xì)胞定位：Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein.蛋白家族：Dermatan-sulfate isomerase family組織特異性：Ubiquitously expressed with higher expression in kidney and ovary and lower expression in brain, colon and thymus. Also expressed in renal cell carcinomas, brain tumors, and in a part of melanomas and adenocarcinomas from organs other than the breast. Exp數(shù)據(jù)庫(kù)鏈接：
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
