DRG2 Antibody

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) DRG2 Polyclonal antibody
Uniprot No.：

P55039
基因名：

DRG2
別名：

Developmentally regulated GTP binding protein 2 antibody; Developmentally-regulated GTP-binding protein 2 antibody; DRG 2 antibody; DRG-2 antibody; drg2 antibody; DRG2_HUMAN antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Developmentally-regulated GTP-binding protein 2 protein (1-364AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，DRG2 Antibody (CSB-PA007186LA01HU)，的標記方式是Non-conjugated。對于DRG2 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA007186LB01HU	DRG2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA007186LC01HU	DRG2 Antibody, FITC conjugated
Biotin	CSB-PA007186LD01HU	DRG2 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. When hydroxylated at C-3 of 'Lys-21' by JMJD7, may bind to RNA and play a role in translation.
基因功能參考文獻：
1. Taken together, our data demonstrate that DRG2 acts as a regulator of mitochondrial fission by controlling the expression of Drp1. PMID: 28363867
2. Authors observed that knockdown of DRG2 in HeLa cells affected growth in a wound-healing assay, and tumorigenicity in nude mice xenografts. PMID: 27669826
3. Results demonstrate that DRG2 is an endosomal protein and a key regulator of Rab5 deactivation and Tfn recycling. PMID: 26582392
4. miR19153p functions as a silencer of apoptosis, which regulates lung cancer apoptosis via targeting DRG2/PBX2. PMID: 26572100
5. Basal expression level of DRG2 is regulated by the Sp1 transcription factor. PMID: 21296692
6. overexpression of DRG2 in Jurkat cells affects genes regulating cell-cycle arrest and apoptosis, and that these molecular changes may be important in the growth or differentiation of cells PMID: 15113831
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亞細胞定位：

Nucleus. Cytoplasm.
蛋白家族：

TRAFAC class OBG-HflX-like GTPase superfamily, OBG GTPase family
組織特異性：

Highest levels in skeletal muscle, heart and kidney. Low levels in colon, thymus, spleen, small intestine, lung and Leukocytes.
數據庫鏈接：

HGNC: 3030

OMIM: 602986

KEGG: hsa:1819

STRING: 9606.ENSP00000225729

UniGene: Hs.78582

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