DNTTIP1 Antibody

說(shuō)明書

中文名稱：

DNTTIP1兔多克隆抗體
貨號(hào)：

CSB-PA007089LA01HU
規(guī)格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA007089LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA007089LA01HU at dilution of 1:100
其他：

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) DNTTIP1 Polyclonal antibody
Uniprot No.：

Q9H147
基因名：

DNTTIP1
別名：

C20orf167 antibody; Deoxynucleotidyltransferase terminal interacting protein 1 antibody; Deoxynucleotidyltransferase terminal-interacting protein 1 antibody; dJ447F3.4 antibody; DNTTIP1 antibody; TdIF 1 antibody; TdIF1 antibody; TDIF1_HUMAN antibody; TdT binding protein antibody; TdT interacting factor 1 antibody; TdT-interacting factor 1 antibody; Terminal deoxynucleotidyltransferase interacting factor 1 antibody; Terminal deoxynucleotidyltransferase-interacting factor 1 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Deoxynucleotidyltransferase terminal-interacting protein 1 protein (1-329AA)
免疫原種屬：

Homo sapiens (Human)

標(biāo)記方式：

Non-conjugated

本頁(yè)面中的產(chǎn)品，DNTTIP1 Antibody (CSB-PA007089LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于DNTTIP1 Antibody，我們還提供其他標(biāo)記。見下表：

標(biāo)記方式	貨號(hào)	產(chǎn)品名稱	應(yīng)用
HRP	CSB-PA007089LB01HU	DNTTIP1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA007089LC01HU	DNTTIP1 Antibody, FITC conjugated
Biotin	CSB-PA007089LD01HU	DNTTIP1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro). Also acts as a transcriptional regulator, binding to the consensus sequence 5'-GNTGCATG-3' following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA.
基因功能參考文獻(xiàn)：
1. In luciferase assays, TdIF1 can up-regulate transcription activity of the promoters containing the TdIF1-binding sequences, and this effect is mainly through the palindrome 5'-TGCATG-3'. PMID: 25619743
2. During cell division, DNTTIP1 is part of the mitotic deacetylase complex MIDAC, which also contains C14ORF43/MIDEAS and HDAC1/HDAC2. PMID: 21258344
3. During cell division, DNTTIP1 forms a complex with C14ORF43/MIDEAS and HDAC1/HDAC2. PMID: 21258344
4. The TdT binding, DNA binding and dimerization regions, and nuclear localization signal (NLS) in TdIF1, were identified. PMID: 17663723
亞細(xì)胞定位：

Nucleus.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 16160

OMIM: 611388

KEGG: hsa:116092

STRING: 9606.ENSP00000361705

UniGene: Hs.472852

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