DNM3 Antibody
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中文名稱：DNM3兔多克隆抗體
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貨號：CSB-PA007080GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：
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別名：testicular dynamin antibody; testicular antibody; DNM 3 antibody; DNM3 antibody; DNM3 protein antibody; Dyn3 antibody; DYN3_HUMAN antibody; Dyna III antibody; DynaIII antibody; dynamin 2 antibody; Dynamin antibody; Dynamin family member antibody; Dynamin testicular antibody; Dynamin-3 antibody; Dynamin3 antibody; EC 3.6.5.5 antibody; KIAA0820 antibody; MGC70433 antibody; T dynamin antibody; T-dynamin antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Human DNM3
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB,IHC
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點詳情
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功能：Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis.
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基因功能參考文獻：
- In glioma, elevated miR-221 expression is a biomarker for glioma. DNM3 is a target of miR-221 and RELA regulates miR-221 expression. PMID: 27837435
- Genetic variability in DNM3 modifies age of onset for LRRK2 Gly2019Ser parkinsonism. PMID: 27692902
- DNM3 may be involved in risk of obsessive-compulsive disorder. PMID: 27023174
- Microdeletion of DNM3 harboring miR199 and miR214 is associated with skeletal abnormalities. PMID: 26333682
- DNM3 attenuates the proliferation and induces apoptosis of gastric cancer cells. PMID: 26784388
- Data show that the classical dynamin DNM1 and DNM3 genes reach their maximum expression levels (100% of maximal expression) in all normal central nervous system tissues studied. PMID: 24673776
- Data indicate that dynamin 3 (DNM3) harbors MEIS1 binding sites and is associated with differences in mean platelet volume (MPV). PMID: 22972982
- DNM3 not only participates in megakaryocyte progenitor amplification, but is also involved in cytoplasmic enlargement and the formation of the demarcation membrane system. PMID: 21671749
- Dynamin GTPase regulation is altered by PH domain mutations found in centronuclear myopathy patients. PMID: 20700106
- dynamin-3 and the postsynaptic adaptor Homer positions the endocytic zones near the postsynaptic density PMID: 17880892
- Upon comparison of PBMC and skin samples of Sezary syndrome versus mycosis fungoides, CDO1 and DNM3 were found upregulated only in Sezary syndrome. PMID: 18033314
- Dynamin 3 participates in the growth and development of megakaryocytes. PMID: 19007685
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亞細胞定位：Cytoplasm. Cytoplasm, cytoskeleton.
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蛋白家族：TRAFAC class dynamin-like GTPase superfamily, Dynamin/Fzo/YdjA family
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數(shù)據(jù)庫鏈接：
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