DNAJB4 Antibody
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中文名稱：DNAJB4兔多克隆抗體
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貨號：CSB-PA007010GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：DNAJB4
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別名：DjB4 antibody; DnaJ (Hsp40) homolog subfamily B member 4 antibody; DnaJ homolog subfamily B member 4 antibody; DnaJ like heat shock protein 40 antibody; DNAJB 4 antibody; DNAJB4 antibody; DNAJW antibody; DNJB4_HUMAN antibody; Heat shock 40 kDa protein 1 homolog antibody; Heat shock protein 40 homolog antibody; HLJ 1 antibody; HLJ1 antibody; HSP40 homolog antibody; Human liver DnaJ-like protein antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human DNAJB4
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC,IF
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
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靶點詳情
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功能：Probable chaperone. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro).
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基因功能參考文獻：
- These new observations support the idea that HLJ1 is a tumor suppressor candidate and potential biomarker for breast cancer PMID: 28481734
- HLJ1 is an endogenous Src inhibitor that can suppress cancer metastasis through complex interacting mechanisms. PMID: 27065329
- HLJ1 is a strong tumor suppressor for colorectal carcinoma PMID: 24696714
- Low expression of DNAJB4 is associated with gastric carcinomas. PMID: 24293545
- Silencing of HLJ1 partially reverses the inhibition of cancer-cell invasion by andrographolide. PMID: 23306212
- HBV could promote HLJ1 expression by up-regulating the transcription factor YY1. PMID: 21345358
- acidic stress increases the association between HLJ1 and beta-actin to modulate migration of human lung cancer cells PMID: 20615403
- HLJ1 switches the role of NPM1, which can act as tumor suppressor or oncogene, by modulating the oligomerization of NPM1 via HLJ1-NPM1 heterodimer formation and recruiting AP-2alpha to the MMP-2 promoter. PMID: 20145123
- Results indicate that DjA1 and DjB4 of subfamilies A and B of human Hsp40 have different quaternary structures and chaperone functions. PMID: 15661747
- The increase in HLJ1 and E-cadherin expression, as well as the suppression of invasion ability, can be reversed specifically by HLJ1 siRNA. PMID: 15782117
- HLJ1 is a novel tumor suppressor in NSCLC, and high HLJ1 expression is associated with reduced cancer recurrence and prolonged survival of NSCLC patients. PMID: 16788156
- Results show that curcumin induces HLJ1, through activation of the JNK/JunD pathway, and inhibits lung cancer cell invasion and metastasis by modulating E-cadherin expression. PMID: 18794131
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亞細胞定位：Cytoplasm. Cell membrane. Note=Cytoplasmic according to PubMed:18837411 and membrane-associated according to PubMed:16542645.
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組織特異性：Expressed in heart, pancreas and skeletal muscle, and to a lesser extent in brain, placenta and liver.
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數據庫鏈接：
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