DNAJB14 Antibody, HRP conjugated
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中文名稱：
DNAJB14兔多克隆抗體, HRP偶聯
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貨號：
CSB-PA819454LB01HU
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規格：
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其他：
產品詳情
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產品名稱：
Rabbit anti-Homo sapiens (Human) DNAJB14 Polyclonal antibody
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Uniprot No.：
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基因名：
DNAJB14
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別名：
DNAJB14; UNQ9427/PRO34683; DnaJ homolog subfamily B member 14
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宿主：
Rabbit
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反應種屬：
Human
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免疫原：
Recombinant Human DnaJ homolog subfamily B member 14 protein (1-244AA)
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免疫原種屬：
Homo sapiens (Human)
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標記方式：
HRP
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克隆類型：
Polyclonal
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抗體亞型：
IgG
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純化方式：
>95%, Protein G purified
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濃度：
It differs from different batches. Please contact us to confirm it.
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保存緩沖液：
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
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產品提供形式：
Liquid
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應用范圍：
ELISA
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Protocols：
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儲存條件：
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶點詳情
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功能：
Acts as a co-chaperone with HSPA8/Hsc70; required to promote protein folding and trafficking, prevent aggregation of client proteins, and promote unfolded proteins to endoplasmic reticulum-associated degradation (ERAD) pathway. Acts by determining HSPA8/Hsc70's ATPase and polypeptide-binding activities. Can also act independently of HSPA8/Hsc70: together with DNAJB12, acts as a chaperone that promotes maturation of potassium channels KCND2 and KCNH2 by stabilizing nascent channel subunits and assembling them into tetramers. While stabilization of nascent channel proteins is dependent on HSPA8/Hsc70, the process of oligomerization of channel subunits is independent of HSPA8/Hsc70. When overexpressed, forms membranous structures together with DNAJB12 and HSPA8/Hsc70 within the nucleus; the role of these structures, named DJANGOs, is still unclear.; (Microbial infection) In case of infection by polyomavirus, involved in the virus endoplasmic reticulum membrane penetration and infection.
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亞細胞定位：
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein.
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蛋白家族：
DnaJ family, DNAJB12/DNAJB14 subfamily
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數據庫鏈接：
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