DMXL2 Antibody

中文名稱：

DMXL2兔多克隆抗體
貨號(hào)：

CSB-PA819469LA01HU
規(guī)格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA819469LA01HU at dilution of 1:100

Immunofluorescent analysis of HepG2 cells using CSB-PA819469LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
其他：

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) DMXL2 Polyclonal antibody
Uniprot No.：

Q8TDJ6
基因名：

DMXL2
別名：

DmX-like protein 2 antibody; Dmxl2 antibody; DMXL2_HUMAN antibody; KIAA0856 antibody; Rabconnectin-3 antibody; RC3 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human DmX-like protein 2 protein (2471-2657AA)
免疫原種屬：

Homo sapiens (Human)

標(biāo)記方式：

Non-conjugated

本頁面中的產(chǎn)品，DMXL2 Antibody (CSB-PA819469LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于DMXL2 Antibody，我們還提供其他標(biāo)記。見下表：

標(biāo)記方式	貨號(hào)	產(chǎn)品名稱	應(yīng)用
HRP	CSB-PA819469LB01HU	DMXL2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA819469LC01HU	DMXL2 Antibody, FITC conjugated
Biotin	CSB-PA819469LD01HU	DMXL2 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, IHC, IF

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May serve as a scaffold protein for MADD and RAB3GA on synaptic vesicles. Plays a role in the brain as a key controller of neuronal and endocrine homeostatic processes.
基因功能參考文獻(xiàn)：
1. Data indicated that the p.Arg2417His variant in DMXL2 is associated with dominant, nonsyndromic hearing loss and suggested an important role of DMXL2 in inner ear function. PMID: 27657680
2. authors demonstrate that DMXL2 is a transmembrane protein with a potential extra-cellular domain. These findings identify DMXL2 as a novel, functional biomarker for ERalpha positive breast cancer. PMID: 26093085
3. Haploinsufficiency of Dmxl2, encoding a synaptic protein, causes infertility associated with a loss of GnRH neurons in humans and mice. PMID: 25248098
4. an important role for Rabconnectin-3 and V-ATPase activity in the Notch signaling pathway in mammalian cells. PMID: 20810660
相關(guān)疾病：

Polyendocrine-polyneuropathy syndrome (PEPNS); Deafness, autosomal dominant, 71 (DFNA71)
亞細(xì)胞定位：

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle.
數(shù)據(jù)庫鏈接：

HGNC: 2938

OMIM: 612186

KEGG: hsa:23312

STRING: 9606.ENSP00000441858

UniGene: Hs.511386

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