DHX32 Antibody

中文名稱：

DHX32兔多克隆抗體
貨號：

CSB-PA748724LA01HU
規格：

￥440
圖片：
Western Blot
All lanes: DHX32 antibody at 10µg/ml + Mouse liver tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 85, 76 kDa
Observed band size: 85 kDa

Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA748724LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA748724LA01HU at dilution of 1:100
其他：

產品詳情
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靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) DHX32 Polyclonal antibody
Uniprot No.：

Q7L7V1
基因名：

DHX32
別名：

3110079L04Rik antibody; AA408140 antibody; Ddx32 antibody; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 antibody; DEAD/H box 32 antibody; DEAD/H helicase like protein 1 antibody; DEAD/H helicase-like protein 1 antibody; DEAH (Asp-Glu-Ala-His) box polypeptide 32 antibody; DEAH box protein 32 antibody; DHLP1 antibody; DHX32 antibody; DHX32_HUMAN antibody; Helicase DDX32 antibody; HuDDX32 antibody; Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 antibody
宿主：

Rabbit
反應種屬：

Human, Mouse
免疫原：

Recombinant Human Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 protein (301-500AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，DHX32 Antibody (CSB-PA748724LA01HU)，的標記方式是Non-conjugated。對于DHX32 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA748724LB01HU	DHX32 Antibody, HRP conjugated	ELISA
FITC	CSB-PA748724LC01HU	DHX32 Antibody, FITC conjugated
Biotin	CSB-PA748724LD01HU	DHX32 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB, IHC

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

基因功能參考文獻：
1. DHX32 is an upstream regulator for beta-catenin, which promotes the activity of beta-catenin to upregulate expression of VEGFA in colorectal cancer cells. Depletion of DHX32 expression suppressed colorectal cancer tumor angiogenesis and tumor growth. PMID: 28330603
2. Structural characterization and expression of the DDX32 gene. Expression studies show that DDX32 is widespread but specifically down-regulated in acute lymphoblastic leukemias and might play a role in normal and/or abnormal lymphopoiesis. PMID: 12163057
3. cloned DHX32 proximal promoter and identified a 218bp fragment containing two potential binding sites for the transcription factor nuclear factor of activated T cells (NF-AT) PMID: 16414036
4. These results suggest that DHX32 is a putative RNA helicase that might be involved in regulating nuclear and mitochondrial gene expression. PMID: 16959245
5. dysregulated expression of DHX32 might lead to as of yet unknown changes in mitochondrial homeostasis manifested by cytoplasmic redistribution of the molecular chaperon Hsp60 PMID: 17174952
6. In peripheral blood lymphocytes, a correlation between DHX32 and c-FLIP short expression was detected in response to different T-cell activation stimuli. Results suggest DHX32 involvement in regulating T-cell response to apoptotic stimuli. PMID: 17352256
7. DHX32 may play an important role in the development of colorectal cancer and could serve as a novel biomarker for colorectal cancer after additional investigation. PMID: 19161603
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亞細胞定位：

Nucleus. Mitochondrion.
蛋白家族：

DEAD box helicase family, DEAH subfamily
組織特異性：

Expressed in lymphoid tissues (at protein level). Expressed in brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung, lymphoid tissues and blood leukocytes.
數據庫鏈接：

HGNC: 16717

OMIM: 607960

KEGG: hsa:55760

STRING: 9606.ENSP00000284690

UniGene: Hs.370292

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