DENND5A Antibody

中文名稱：

DENND5A兔多克隆抗體
貨號：

CSB-PA757108LA01HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA757108LA01HU at dilution of 1:100
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) DENND5A Polyclonal antibody
Uniprot No.：

Q6IQ26
基因名：

DENND5A
別名：

DENND5A antibody; KIAA1091 antibody; RAB6IP1DENN domain-containing protein 5A antibody; Rab6-interacting protein 1 antibody; Rab6IP1 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human DENN domain-containing protein 5A protein (1-300AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，DENND5A Antibody (CSB-PA757108LA01HU)，的標記方式是Non-conjugated。對于DENND5A Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA757108LB01HU	DENND5A Antibody, HRP conjugated	ELISA
FITC	CSB-PA757108LC01HU	DENND5A Antibody, FITC conjugated
Biotin	CSB-PA757108LD01HU	DENND5A Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Involved in the negative regulation of neurite outgrowth.
基因功能參考文獻：
1. identification of an epileptic encephalopathy additionally featuring cerebral calcifications and coarse facial features caused by recessive loss-of-function mutations in DENND5A PMID: 27866705
2. A RUN Domain from DENND5/Rab6IP1 binds sorting Nexin 1 and is involved in the trafficking of vesicles at the level of Golgi. PMID: 22558185
3. crystal structure of Rab6a(GTP) in complex with a 378-residue internal fragment of the effector Rab6IP1 was solved at 3.2 angstroms resolution. This Rab6IP1 region encompasses an all alpha-helical RUN domain followed in tandem by a PLAT domain PMID: 19141279
相關疾?。?/div>
Epileptic encephalopathy, early infantile, 49 (EIEE49)
亞細胞定位：

Golgi apparatus membrane.
蛋白家族：

RAB6IP1 family
數據庫鏈接：

HGNC: 19344

OMIM: 617278

KEGG: hsa:23258

STRING: 9606.ENSP00000328524

UniGene: Hs.501857

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