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中文名稱：DBP兔多克隆抗體
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貨號：CSB-PA365892ZA01HIL
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規格：￥440
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圖片：
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Western Blot
Positive WB detected in Recombinant protein
All lanes: DBP antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 43.5 kDa
Observed band size: 49 kDa
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其他：
產品詳情
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產品描述：
The DBP polyclonal antibody is a rabbit-derived antibody that has been specifically designed to target the DBP protein. The immunogen used to generate this DBP antibody is a recombinant human adenovirus C serotype 5 DBP protein (174-529aa). The Adenovirus C Serotype 5 DBP is a key regulatory protein in the adenovirus DNA replication and packaging.
DBP mainly functions is to bind to the viral DNA and regulate the transcription of viral genes. It can interact with specific DNA sequences within the adenovirus genome and recruit other viral and cellular proteins to control the timing and efficiency of viral gene expression. This DBP antibody has been purified using protein A/G affinity chromatography. It has been validated for use in two applications, including ELISA and WB. And it shows reactivity with human adenovirus C serotype 5 samples.
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Uniprot No.：
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基因名：
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別名：DNA-binding protein (DBP) (Early 2A protein) (Early E2A DNA-binding protein), DBP
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反應種屬：Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
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免疫原：Recombinant Human adenovirus C serotype 5 DNA-binding protein (DBP), partial (174-529AA)
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免疫原種屬：Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Protein G
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
引用文獻
- Characterization of the function of Adenovirus L4 gene products and their impact on AAV vector production Y Nie, H Pan, Q Li, H Na, B Figueroa,Molecular Therapy Methods & Clinical Development,2024
- A novel role for the adenovirus L4 region 22K and 33K proteins in adeno-associated virus production A Adsero,Human gene therapy,2023
產品評價
相關產品
靶點詳情
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功能：Plays a role in the elongation phase of viral strand displacement replication by unwinding the template in an ATP-independent fashion, employing its capacity to form multimers. Also enhances the rate of initiation. Released from template upon second strand synthesis. Assembles in complex with viral pTP, viral pol, host NFIA and host POU2F1/OCT1 on viral origin of replication. Covers the whole ssDNA genome during synthesis. The complementary strand synthesis induces its relese from DNA template. May inhibit cellular transcription mediated by the interaction between host SRCAP and CBP.
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亞細胞定位：Host nucleus.
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蛋白家族：Adenoviridae E2A DNA-binding protein family
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