DAZAP2 Antibody, FITC conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) DAZAP2 Polyclonal antibody
Uniprot No.：

Q15038
基因名：

DAZAP2
別名：

DAZAP2 antibody; KIAA0058DAZ-associated protein 2 antibody; Deleted in azoospermia-associated protein 2 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human DAZ-associated protein 2 protein (1-168AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

FITC
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

基因功能參考文獻：
1. methylation of DAZAP2 promoter was involved in downregulation of DAZAP2 in multiple myeloma cells. PMID: 22792345
2. In summary we established a new mechanism of IL17RB regulation-Smurf2 dependent degradation of its adaptor protein DAZAP2. PMID: 22070932
3. Lys residues might play important roles in regulating the intracellular dynamics of the PRTB protein.K153 in human PRTB is essential for its ubiquitin-dependent degradation PMID: 21274613
4. DAZAP2 is downregulated in multiple myeloma samples and it may be a signal molecule in multiple myeloma cells. DAZAP2 is involved in the pathogenesis of MM PMID: 17935665
亞細胞定位：

Cytoplasm. Nucleus. Note=Predominantly nuclear in macrophages, stimulation of IL17RB with its ligand IL17E induces accumulation in the cytoplasm.
組織特異性：

Widely expressed. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes. Down-regulated in multiple myeloma.
數據庫鏈接：

HGNC: 2684

OMIM: 607431

KEGG: hsa:9802

STRING: 9606.ENSP00000448051

UniGene: Hs.369761

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