DAP3 Antibody

說明書

中文名稱：

DAP3兔多克隆抗體
貨號：

CSB-PA006497ESR2HU
規格：

￥440
圖片：
Western blot
All lanes: 28S ribosomal protein S29, mitochondrial antibody at 10μg/ml
Lane 1: Hela whole cell lysate
Lane 2: 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 46, 42 kDa
Observed band size: 46 kDa

Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA006497ESR2HU at dilution of 1:100
其他：

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靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) DAP3 Polyclonal antibody
Uniprot No.：

P51398
基因名：

DAP3
別名：

28S ribosomal protein S29 antibody; 28S ribosomal protein S29 mitochondrial antibody; bMRP10 antibody; DAP 3 antibody; DAP-3 antibody; Dap3 antibody; Death associated protein 3 antibody; Death-associated protein 3 antibody; DKFZp686G12159 antibody; FLJ12817 antibody; Ionizing radiation resistance conferring protein antibody; MGC126058 antibody; MGC126059 antibody; Mitochondrial 28S ribosomal protein S29 antibody; mitochondrial antibody; MITOCHONDRIAL RIBOSOMAL PROTEIN S29 antibody; MRP S29 antibody; MRP-S29 antibody; MRPS29 antibody; OTTHUMP00000033480 antibody; OTTHUMP00000033481 antibody; PSD-95/SAP90-binding protein 3 antibody; RT29_HUMAN antibody; S29mt antibody; SAP90/PSD-95-associated protein 3 antibody; SAPAP3 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human 28S ribosomal protein S29, mitochondrial protein (159-398AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
產品提供形式：

Liquid
應用范圍：

ELISA, WB, IHC

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:20-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Involved in mediating interferon-gamma-induced cell death.
基因功能參考文獻：
1. DAP3 plays important roles in mitochondrial function and dynamics PMID: 26306039
2. DAP3 silencing contributes to breast carcinogenesis. PMID: 25738636
3. Knockdown of DAP3 expression promoted cell migration. PMID: 24300973
4. Study demonstrates an inverse association between DAP3 mRNA levels and tumour stage and clinical outcome in breast cancer. PMID: 22287761
5. identified a novel DAP3-binding protein termed death ligand signal enhancer (DELE); results demonstrated the biological significance of DELE for apoptosis signal mediated by death receptors PMID: 20563667
6. show that interferon-beta promoter stimulator 1 (IPS-1) binds DAP3 and induces anoikis by caspase activation. PMID: 19644511
7. Functional interaction between the pro-apoptotic DAP3 and the glucocorticoid receptor PMID: 12099703
8. not involved in TRAIL-induced apoptosis PMID: 12359235
9. DAP3 has a role in the molecular pathway that culminates in fragmented mitochondria PMID: 15175341
10. DAP3 gene might be associated with the mechanisms responsible for adult bronchial asthma and contribute to airway inflammation and remodeling PMID: 15179560
11. DAP3 has a role in anoikis signaling and in apoptosis induction caused by cell detachment PMID: 15302871
12. High DAP3 expression is correlated with thymoma stage PMID: 15679048
13. study investigated the phosphorylation status of ribosomal DAP3 and mapped the phosphorylation sites by tandem mass spectrometry PMID: 18227431
14. Complex I and DAP3, hNOA1 may play a role in mitochondrial respiration and apoptosis. PMID: 19103604
15. DAP3 may participate in mitochondrial maintenance and play a role in the balance between mitochondrial homoeostasis and tumourigenesis in thyroid oncocytic tumors. PMID: 19536094
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亞細胞定位：

Mitochondrion.
蛋白家族：

Mitochondrion-specific ribosomal protein mS29 family
組織特異性：

Ubiquitous.
數據庫鏈接：

HGNC: 2673

OMIM: 602074

KEGG: hsa:7818

STRING: 9606.ENSP00000341692

UniGene: Hs.516746

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