Cleaved-CTSV (L114) Antibody
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中文名稱：Cleaved-CTSV (L114)兔多克隆抗體
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貨號：CSB-PA000037
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規格：￥1090
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圖片：
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Western Blot analysis of HeLa cells using Cleaved-Cathepsin L2 (L114) Polyclonal Antibody
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：CAT L2 antibody; Cathepsin L2 antibody; Cathepsin U antibody; Cathepsin V antibody; CathepsinL2 antibody; CathepsinU antibody; CathepsinV antibody; CATL 2 antibody; CATL2 antibody; CATL2_HUMAN antibody; CTS L2 antibody; CTS U antibody; CTS V antibody; CTSL 2 antibody; CTSL2 antibody; CTSU antibody; CTSV antibody; MGC125957 antibody; PRO305 antibody; UNQ268 antibody
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宿主：Rabbit
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反應種屬：Human,Monkey
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免疫原：Synthesized peptide derived from the Internal region of Human Cathepsin L2.
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：WB, ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 ELISA 1:20000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Cysteine protease. May have an important role in corneal physiology.
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基因功能參考文獻：
- CTSV is involved in melanosome degradation. PMID: 29654760
- exogenous CTSV inhibited Ang -induced hypertrophy in HCM cells by inhibiting PI3K/Akt/mTOR PMID: 28522343
- Cathepsins V and S may serve as auxiliary diagnostic and/or prognostic markers in thymic epithelial tumors. PMID: 27771373
- E2F1 directly binds to CTSL2 promoter and regulates CTSL2 gene expression. PMID: 23542171
- using cathepsin V and cathepsin L as model enzymes, a series of chimeras were generated to identify noncatalytic regions that are responsible for the potent elastolytic activity of cathepsin V PMID: 24121514
- Cathepsin V expression contributes to the development of dermal fibrosis and vasculopathy in systemic sclerosis. PMID: 23287360
- functions of cathepsin V are controlled by N-glycosylation PMID: 22967898
- Findings indicate the unique function of cathepsin V for producing enkephalin and neuropeptide Y (NPY) neuropeptides required for neurotransmission in health and neurological diseases. PMID: 22393040
- CTSL2 might be involved in progression of endometrial cancer. PMID: 22452389
- A proteolytically active variant of cathepsin V is localized to cell nucleus (in peri-nucleolar pattern) in thyroid carcinoma cells. PMID: 20536394
- stratum corneum thiol protease is identical with the recently described cathepsin L2 protease. PMID: 12648222
- Cathepsin V is involved in the degradation of invariant chain in human thymus PMID: 12925692
- Cathepsin V has an elastolytic activity and is expressed in activated macrophages PMID: 15192101
- Human cathepsin V compensates for murine cathepsin L in mouse epidermis and hair follicles. PMID: 15679121
- propeptide was found to behave as a tight-binding inhibitor against CatV PMID: 17516850
- Associated with type 1 diabetes and early-onset myasthenia gravis. PMID: 17869649
- angiogenesis inhibition activity on endothelial cells caused by plasminogen processing by cathepsin V PMID: 18163891
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亞細胞定位：Lysosome.
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蛋白家族：Peptidase C1 family
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組織特異性：Predominantly expressed in the thymus and testis. Also expressed in corneal epithelium, and to a lesser extent in conjunctival epithelium and skin.
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數據庫鏈接：
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