CYP4F22 Antibody
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中文名稱：CYP4F22兔多克隆抗體
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貨號：CSB-PA740654LA01HU
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規(guī)格：￥440
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圖片：
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Western Blot
Positive WB detected in: HEK293 whole cell lysate, Hela whole cell lysate, MCF-7 whole cell lysate, HepG2 whole cell lysate, A549 whole cell lysate
All lanes: CYP4F22 antibody at 3.2µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 62 kDa
Observed band size: 62 kDa
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) CYP4F22 Polyclonal antibody
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Uniprot No.：
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基因名：CYP4F22
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別名：CYP4F22Cytochrome P450 4F22 antibody; EC 1.14.14.- antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Cytochrome P450 4F22 protein (413-507AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產(chǎn)品，CYP4F22 Antibody (CSB-PA740654LA01HU)，的標記方式是Non-conjugated。對于CYP4F22 Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式：Liquid
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應用范圍：ELISA, WB
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:5000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關產(chǎn)品
靶點詳情
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功能：A cytochrome P450 monooxygenase involved in epidermal ceramide biosynthesis. Hydroxylates the terminal carbon (omega-hydroxylation) of ultra-long-chain fatty acyls (C28-C36) prior to ceramide synthesis. Contributes to the synthesis of three classes of omega-hydroxy-ultra-long chain fatty acylceramides having sphingosine, 6-hydroxysphingosine and phytosphingosine bases, all major lipid components that underlie the permeability barrier of the stratum corneum. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
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基因功能參考文獻：
- patients carrying one or two truncating CYP4F22 mutations affecting the SBRs tend to develop collodion membrane at birth PMID: 27735052
- We report two cases of Congenital Ichthyosiform Erythroderma showing homozygous mutations in the gene CYP4F22. PMID: 26646773
- description of CYP4F22 mutations from a Japanese collodion baby with lamellar ichthyosis [case report] PMID: 23871423
- Letter: CYP4F22 is highly expressed at the site and timing of onset of keratinization during skin development. PMID: 22209317
- REVIEW: genetic analyses have identified a wide spectrum of mutations in the CYP4V2gene from patients suffering from Bietti's crystalline corneoretinal dystrophy, and mutations in theCYP4F22 gene have been linked to lamellar ichthyosis PMID: 21540472
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相關疾病：Ichthyosis, congenital, autosomal recessive 5 (ARCI5)
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亞細胞定位：Endoplasmic reticulum membrane; Single-pass type I membrane protein. Microsome membrane; Single-pass type I membrane protein.
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蛋白家族：Cytochrome P450 family
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數(shù)據(jù)庫鏈接：
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