CST5 Antibody, Biotin conjugated

說明書

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) CST5 Polyclonal antibody
Uniprot No.：

P28325
基因名：

CST5
別名：

CST 5 antibody; CST5 antibody; Cystatin 5 antibody; Cystatin-5 antibody; Cystatin-D antibody; CystatinD antibody; Cysteine proteinase inhibitor antibody; CYTD_HUMAN antibody; MGC71922 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Cystatin-D protein (21-142AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Cysteine proteinase inhibitor that possibly plays a protective role against proteinases present in the oral cavity. The order of preference for inhibition is cathepsin S > cathepsin H > cathepsin L > cathepsin B.
基因功能參考文獻：
1. Results imply CST5 as an important mediator of tumor suppression by p53 in colorectal cancer. PMID: 26158294
2. These results support an unanticipated role of cystatin D in the cell nucleus, controlling the transcription of specific genes involved in crucial cellular functions, which may mediate its protective action in colon cancer. PMID: 26364852
3. Compared with its homologues, cystatin D presents an unusual inhibition profile with a preferential inhibition cathepsin S > cathepsin H > cathepsin L and no inhibition of cathepsin B or pig legumain. PMID: 15728581
4. Cystatin D is a candidate tumor suppressor gene induced by vitamin D in human colon cancer cells. PMID: 19662683
亞細胞定位：

Secreted.
蛋白家族：

Cystatin family
組織特異性：

Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in parotid gland but not in seminal vesicle, prostate, epididymis, testis, ovary, placenta, thyroid, gastric corpus, small intestine, liver, or gall b
數(shù)據(jù)庫鏈接：

HGNC: 2477

OMIM: 123858

KEGG: hsa:1473

STRING: 9606.ENSP00000307132

UniGene: Hs.121489

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