CSMD3 Antibody

中文名稱：

CSMD3兔多克隆抗體
貨號：

CSB-PA800102LA01HU
規(guī)格：

￥440
圖片：
IHC image of CSB-PA800102LA01HU diluted at 1:400 and staining in paraffin-embedded human cervical cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Immunofluorescence staining of HepG2 cells with CSB-PA800102LA01HU at 1: 133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized tissue using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C.The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) .
其他：

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) CSMD3 Polyclonal antibody
Uniprot No.：

Q7Z407
基因名：

CSMD3
別名：

CSMD3 antibody; KIAA1894CUB and sushi domain-containing protein 3 antibody; CUB and sushi multiple domains protein 3 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human CUB and sushi domain-containing protein 3 protein (233-380AA)
免疫原種屬：

Homo sapiens (Human)

標(biāo)記方式：

Non-conjugated

本頁面中的產(chǎn)品，CSMD3 Antibody (CSB-PA800102LA01HU)，的標(biāo)記方式是Non-conjugated。對于CSMD3 Antibody，我們還提供其他標(biāo)記。見下表：

標(biāo)記方式	貨號	產(chǎn)品名稱	應(yīng)用
HRP	CSB-PA800102LB01HU	CSMD3 Antibody, HRP conjugated	ELISA
FITC	CSB-PA800102LC01HU	CSMD3 Antibody, FITC conjugated
Biotin	CSB-PA800102LD01HU	CSMD3 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, IHC, IF

推薦稀釋比：

Application	Recommended Dilution
IHC	1:200-1:500
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Involved in dendrite development.
基因功能參考文獻(xiàn)：
1. Nonsynonymous variants of CSMD3 is associated with familial colorectal cancer. PMID: 21351276
2. CSMD3 encodes a protein with CUB and sushi multiple domains and is a candidate gene for benign adult familial myoclonic epilepsy on human chromosome 8q23.3-q24.1 PMID: 12943675
3. Breakpoints on chromosomes 8 in both patients do not interrupt any known gene but both map in a region containing the CSMD3 gene, which thereby can be considered as a candidate for autistic spectrum disorders PMID: 18270536
4. Single-nucleotide polymorphisms in CSMD3 is associated with prostate cancer risk in hispanic men. PMID: 19528667
5. CSMD3 is deleted in a subject with combined tricho-rhino-phalangeal syndrome II with mental retardation and growth hormone deficiency. PMID: 15523607
6. CSMD3 protein domain structure and the sequence of the cytoplasmic tail are highly conserved between mammals and fish. PMID: 12906867
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亞細(xì)胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

CSMD family
組織特異性：

Weakly expressed in most tissues, except in brain. Expressed at intermediate level in brain, including cerebellum, substantia nigra, thalamus, spinal cord, hippocampus and fetal brain. Also expressed in testis.
數(shù)據(jù)庫鏈接：

HGNC: 19291

OMIM: 608399

KEGG: hsa:114788

STRING: 9606.ENSP00000297405

UniGene: Hs.91381

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