COPS7A Antibody

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) COPS7A Polyclonal antibody
Uniprot No.：

Q9UBW8
基因名：

COPS7A
別名：

COP9 complex subunit 7a antibody; COP9 constitutive photomorphogenic homolog subunit 7A antibody; COP9 signalosome complex subunit 7a antibody; COP9 signalosome subunit 7A antibody; COPS7A antibody; CSN7A antibody; CSN7A_HUMAN antibody; Dermal papilla derived protein 10 antibody; Dermal papilla-derived protein 10 antibody; DERP10 antibody; JAB1 containing signalosome subunit 7a antibody; JAB1-containing signalosome subunit 7a antibody; SGN7a antibody; Signalosome subunit 7a antibody
宿主：

Rabbit
反應種屬：

Human, Mouse
免疫原：

Recombinant Human COP9 signalosome complex subunit 7a protein (2-275AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，COPS7A Antibody (CSB-PA880068HA01HU)，的標記方式是Non-conjugated。對于COPS7A Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA880068HB01HU	COPS7A Antibody, HRP conjugated	ELISA
FITC	CSB-PA880068HC01HU	COPS7A Antibody, FITC conjugated
Biotin	CSB-PA880068HD01HU	COPS7A Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB, IHC

推薦稀釋比：

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
亞細胞定位：

Cytoplasm. Nucleus.
蛋白家族：

CSN7/EIF3M family, CSN7 subfamily
組織特異性：

Widely expressed. Expressed at high level in brain, heart and skeletal muscle.
數據庫鏈接：

HGNC: 16758

OMIM: 616009

KEGG: hsa:50813

STRING: 9606.ENSP00000229251

UniGene: Hs.530823

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