CNKSR3 Antibody, FITC conjugated
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中文名稱：CNKSR3兔多克隆抗體, FITC偶聯
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貨號：CSB-PA757602LC01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) CNKSR3 Polyclonal antibody
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Uniprot No.：
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基因名：CNKSR3
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別名：CNKSR3 antibody; MAGI1Connector enhancer of kinase suppressor of ras 3 antibody; Connector enhancer of KSR 3 antibody; CNK homolog protein 3 antibody; CNK3 antibody; CNKSR family member 3 antibody; Maguin-like protein antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Connector enhancer of kinase suppressor of ras 3 protein (301-555AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Involved in transepithelial sodium transport. Regulates aldosterone-induced and epithelial sodium channel (ENaC)-mediated sodium transport through regulation of ENaC cell surface expression. Acts as a scaffold protein coordinating the assembly of an ENaC-regulatory complex (ERC).
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基因功能參考文獻：
- SCAF8-CNKSR3 variant rs955333 was not associated with diabetic kidney disease but showed association with diabetic retinopathy in Chinese type 2 diabetes patients PMID: 28401168
- Cox regression and Kaplan-Meier survival analysis identified that amplification of the CNKSR3 gene (log-rank, P = 0.022) with an associated increase in its protein expression (log-rank, P = 0.011) correlated with longer patient survival. PMID: 23357503
- CNK3 is a molecular scaffold, which coordinates the assembly of a multiprotein ENaC-regulatory complex and hence plays a central role in Na(+) homeostasis. PMID: 22851176
- two gene markers (CNKSR3 and SPTBN2) differentiate between aspirin-exacerbated respiratory disease and aspirin-tolerant asthma with a perfect discriminative power PMID: 22457146
- CNK3 and IPCEF1 produce a single protein that is required for HGF dependent Arf6 activation and migration. PMID: 22085542
- CNKSR3, a homologue of scaffold proteins involved in MAPK pathway regulation, is a direct target of MR and is required for the maintenance of transepithelial sodium transport in the kidney. PMID: 19567370
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亞細胞定位：Cytoplasm. Apical cell membrane; Peripheral membrane protein.
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蛋白家族：CNKSR family
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數據庫鏈接：
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