CMTM3 Antibody
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中文名稱：CMTM3兔多克隆抗體
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貨號(hào)：CSB-PA001727
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規(guī)格：￥1090
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圖片：
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Western Blot analysis of COS7 cells using CMTM3 Polyclonal Antibody
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：CMTM3
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別名：CMTM3; CKLFSF3; CKLF-like MARVEL transmembrane domain-containing protein 3; Chemokine-like factor superfamily member 3
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宿主：Rabbit
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反應(yīng)種屬：Human,Monkey
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免疫原：Synthesized peptide derived from the N-terminal region of Human CMTM3.
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：WB, ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 ELISA 1:40000 -
Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點(diǎn)詳情
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基因功能參考文獻(xiàn)：
- CMTM3 exhibited a lower expression pattern in gastric cancer tissues.MiR-135b-5p promotes gastric cancer progression by targeting CMTM3. PMID: 29345297
- this study demonstrates that knockdown of CMTM3 promotes the metastasis of gastric cancer through the STAT3/Twist1/EMT pathway PMID: 27121055
- CMTM3 was significantly hypermethylated in colorectal cancer tissues when compared with adjacent normal colorectal tissues. PMID: 28782576
- CMTM3 decreases EGFR expression, facilitates EGFR degradation, and inhibits the EGF-mediated tumorigenicity of gastric cancer cells by enhancing Rab5 activity. PMID: 27867015
- CMTM3 mediates cell-cell adhesion at adherens junctions and contributes to the control of vascular sprouting by regulation VE-cadherin turnover. PMID: 28428220
- Overexpression of CMTM3 attenuated the tumor growth of hepatocellular carcinoma. PMID: 27629543
- identified CMTM3 as a novel secretory protein released via exosomes in the prostate PMID: 27125975
- study indicates that elevated CMTM3 methylation is a risk factor in male LSCC patients, especially in the patients with age over 55years and with smoking behavior PMID: 27521994
- Reduced expression of CMTM3 is associated with prostate cancer. PMID: 25990505
- Low expression of CMTM3 was associated with metastasis and recurrence of oral squamous cell carcinoma. PMID: 25946973
- CMTM3 is significantly down-regulated in clear cell renal cell carcinoma and exerts remarkable tumor-suppressive functions PMID: 23907292
- Peritoneal disseminated metastases were significantly suppressed by CMTM3. PMID: 24131472
- CMTM3/CKLFSF3 is an evolutionarily conserved gene that may have important roles in the male reproductive system and immune system. PMID: 17002874
- CMTM3 inhibits prostate-specific antigen expression at both mRNA and protein levels with no obvious influence on androgen receptor expression. PMID: 18402773
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亞細(xì)胞定位：Membrane; Multi-pass membrane protein.
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蛋白家族：Chemokine-like factor family
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組織特異性：Expressed in the leukocytes, placenta and testis.
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數(shù)據(jù)庫(kù)鏈接：
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