CLTA Antibody
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中文名稱：CLTA兔多克隆抗體
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貨號：CSB-PA005591DSR2HU
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規格：￥440
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圖片：
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Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA005591DSR2HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA005591DSR2HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) CLTA Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：Clathrin light chain A antibody; Clathrin light chain B antibody; Clathrin light chain LCA antibody; Clathrin light chain LCB antibody; Clathrin light polypeptide A antibody; Clathrin light polypeptide antibody; Clathrin light polypeptide B antibody; Clathrin light polypeptide LCA antibody; Clathrin light polypeptide LCB antibody; Clathrin; light chain (Lcb) antibody; Clathrin; light polypeptide (Lca) antibody; Clathrin; light polypeptide (Lcb) antibody; CLCA_HUMAN antibody; CLTA antibody; CLTB antibody; Lca antibody; LCB antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Clathrin light chain A protein (1-218AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge.
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基因功能參考文獻：
- Data indicate that clathrin-mediated endocytosis of proto-oncogene protein erbB-3 (ErbB3) is depending on epsin-1. PMID: 26975582
- Upon receptor activation, prostate alpha1A-adrenoceptors bind clathrin LCA. PMID: 23460120
- upon ligand activation, CysLT(1)R is tyrosine-phosphorylated and released from heterodimers with CysLT(2)R and, subsequently, internalizes from the plasma membrane to the nuclear membrane in a clathrin-, arrestin-3-, and Rab-5-dependent manner PMID: 21203429
- Data show that MAD2B interacts with CLTA during the G2/M phase of the cell cycle and that depletion of MAD2B leads to a marked increase in the percentage of misaligned chromosomes and a redistribution of CLTA during mitosis. PMID: 21152103
- Human Rhinovirus 2 uses clathrin-mediated endocytosis to infect cells PMID: 12692238
- Data suggest that clathrin heavy chains bound to light chains (LC) a and b contribute to pit formation, but the affinity of LCa-free HC in pits is reduced, and the Ca(2+)- and ATP-mediated control of clathrin function is lost. PMID: 16138905
- in mammalian cells CLCs function in intracellular membrane trafficking by acting as recruitment proteins for HIP1R, enabling HIP1R to regulate actin assembly on clathrin-coated structures PMID: 18165318
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亞細胞定位：Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, spindle.
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蛋白家族：Clathrin light chain family
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數據庫鏈接：
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