CLCN6 Antibody

說明書

中文名稱：

CLCN6兔多克隆抗體
貨號：

CSB-PA001679
規(guī)格：

￥1090
圖片：
Western Blot analysis of L929 cells using CLC-6 Polyclonal Antibody

Western Blot analysis of K562 cells using CLC-6 Polyclonal Antibody
其他：

產(chǎn)品詳情

Uniprot No.：

P51797
基因名：

CLCN6
別名：

Chloride channel 6 antibody; Chloride channel protein 6 antibody; Chloride channel voltage sensitive 6 antibody; Chloride transport protein 6 antibody; ClC 6 antibody; ClC-6 antibody; ClC6 antibody; CLCN6 antibody; CLCN6_HUMAN antibody; KIAA0046 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat,Monkey
免疫原：

Synthesized peptide derived from the Internal region of Human CLC-6.
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

WB, ELISA

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:40000

Protocols：

Western Blotting (WB) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Chloride transport protein, initially identified as voltage-gated chloride channel. The presence of the conserved gating glutamate residues suggests that is functions as antiporter.
基因功能參考文獻：
1. These findings implicate the effect of rare coding variants in CLCN6 in Blood Pressure variation and offer new insights into Blood Pressure regulation. PMID: 26658788
2. A non-synonymous single nucleotide variation (SNV) was identified in the voltage-sensitive chloride channel 6 gene. PMID: 25794116
3. late endosomal ClC-6 mediates proton/chloride countertransport in heterologous plasma membrane expression PMID: 20466723
4. differential sorting of endogenous (late endosomal) versus overexpressed (early and recycling endosomal) ClC-6 is reminiscent of that of other late endosomal/lysosomal membrane proteins PMID: 17534424
亞細胞定位：

Endosome membrane; Multi-pass membrane protein. Note=Detected in detergent-resistant lipid rafts.
蛋白家族：

Chloride channel (TC 2.A.49) family, ClC-6/CLCN6 subfamily
組織特異性：

Testis, ovary, small intestine, brain and skeletal muscle. Low level expression in aortic and coronary vascular smooth muscle cells, and aortic endothelial cells. Isoform 3 is only detected in kidney.
數(shù)據(jù)庫鏈接：

HGNC: 2024

OMIM: 602726

KEGG: hsa:1185

STRING: 9606.ENSP00000234488

UniGene: Hs.193043

YWHAG Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC

Species Reactivity: Human
YWHAB Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC, IF, FC

Species Reactivity: Human, Mouse, Rat
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC

Species Reactivity: Human
XRCC5 Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC, IF

Species Reactivity: Human
XPNPEP1 Recombinant Monoclonal Antibody

Applications: ELISA, IHC, FC

Species Reactivity: Human
XDH Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC

Species Reactivity: Human
WT1 Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC

Species Reactivity: Human
WFDC2 Recombinant Monoclonal Antibody

Applications: ELISA, WB, FC

Species Reactivity: Human