CLCF1 Antibody
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中文名稱：CLCF1兔多克隆抗體
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貨號：CSB-PA906951LA01HU
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規(guī)格：￥440
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圖片：
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IHC image of CSB-PA906951LA01HU diluted at 1:200 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) CLCF1 Polyclonal antibody
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Uniprot No.：
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基因名：CLCF1
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別名：B cell stimulating factor 3 antibody; B-cell-stimulating factor 3 antibody; BSF 3 antibody; BSF-3 antibody; BSF3 antibody; Cardiotrophin like cytokine antibody; Cardiotrophin like cytokine factor 1 antibody; Cardiotrophin-like cytokine factor 1 antibody; CISS 2 antibody; CISS2 antibody; CLC antibody; CLCF 1 antibody; Clcf1 antibody; CLCF1_HUMAN antibody; Cold induced sweating syndrome 2 antibody; CRLF 1 associated cytokine like factor 1 antibody; CRLF1 associated cytokine like factor 1 antibody; Neurotrophin 1 antibody; Neurotrophin 1/B cell stimulating factor 3 antibody; Neurotrophin1 antibody; NNT 1 antibody; NNT-1 antibody; Novel neurotrophin 1 antibody; Novel neurotrophin-1 antibody; NR 6 antibody; NR6 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Cardiotrophin-like cytokine factor 1 protein (28-178AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產(chǎn)品，CLCF1 Antibody (CSB-PA906951LA01HU)，的標記方式是Non-conjugated。對于CLCF1 Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式：Liquid
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應用范圍：ELISA, IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:200-1:500 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關產(chǎn)品
靶點詳情
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功能：In complex with CRLF1, forms a heterodimeric neurotropic cytokine that plays a crucial role during neuronal development (Probable). Also stimulates B-cells. Binds to and activates the ILST/gp130 receptor.
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基因功能參考文獻：
- CLF-1, based on its binding site for CLC and on two additional and independent sites for CNTFRalpha and sorLA, is a key player in CLC and CNTFRalpha signaling and turnover. PMID: 26858303
- Cardiotrophin-like cytokine factor 1 (CLCF1) and neuropoietin (NP) signalling and their roles in development, adulthood, cancer and degenerative disorders. PMID: 26198769
- albuminuria in focal segmental glomerulosclerosis is related to qualitative or quantitative changes in the CLCF1-CRLF1 complex. PMID: 25843671
- activation of the Jak-STAT cascade is essential for corticotroph NNT-1/BSF-3 signaling. PMID: 12639901
- Structural and docking interaction studies showed that the R197L substitution destabilized the contact site between CLC and CNTFRalpha. PMID: 16782820
- Ciliary neurotrophic factor, cardiotrophin-like cytokine, and neuropoietin share a conserved binding site on the ciliary neurotrophic factor receptor alpha chain PMID: 18728012
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相關疾病：Cold-induced sweating syndrome 2 (CISS2)
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亞細胞定位：Secreted.
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蛋白家族：IL-6 superfamily
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組織特異性：Expressed predominantly in lymph nodes, spleen, peripheral blood lymphocytes, bone marrow, and fetal liver.
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數(shù)據(jù)庫鏈接：
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