CKMT1A Antibody

中文名稱：

CKMT1A兔多克隆抗體
貨號：

CSB-PA09817A0Rb
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA09817A0Rb at dilution of 1:100

Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA09817A0Rb at dilution of 1:100

Immunofluorescent analysis of MCF-7 cells using CSB-PA09817A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) CKMT1A Polyclonal antibody
Uniprot No.：

P12532
基因名：

CKMT1A
別名：

Acidic-type mitochondrial creatine kinase antibody; CKMT antibody; CKMT1 antibody; CKMT1B antibody; Creatine kinase mitochondrial 1 (ubiquitous) antibody; Creatine kinase mitochondrial 1B antibody; Creatine kinase U type mitochondrial antibody; Creatine kinase U-type antibody; KCRU_HUMAN antibody; Mia-CK antibody; mitochondrial antibody; U-MtCK antibody; Ubiquitous mitochondrial creatine kinase antibody; UMTCK antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Creatine kinase U-type, mitochondrial protein (40-417AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，CKMT1A Antibody (CSB-PA09817A0Rb)，的標記方式是Non-conjugated。對于CKMT1A Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA09817B0Rb	CKMT1A Antibody, HRP conjugated	ELISA
FITC	CSB-PA09817C0Rb	CKMT1A Antibody, FITC conjugated
Biotin	CSB-PA09817D0Rb	CKMT1A Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC, IF

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
基因功能參考文獻：
1. The highly conserved residue E227 acts as the catalytic base to accept the guanidinium proton transferred from creatine in UMTCK. PMID: 27909311
2. Mitochondrial creatine kinase CKMT1 is necessary for survival of EVI1-expressing cells in subjects with EVI1-positive AML. PMID: 28191887
3. LRRK2 can interact directly with uMtCK to block its entry into mitochondria and its subsequent processing. PMID: 21370995
4. CKMT1 is a key regulator of the permeability transition pore through a complex that is distinct from the classical permeability transition pore. PMID: 24522192
5. mitochondrial creatine kinase expression in hepatocellular carcinoma may be caused by hepatocarcinogenesis per se but not by loss of mitochondrial integrity, of which ASB9 could be a negative regulator PMID: 24174293
6. The results indicated that uMtCK expression is associated with a poor prognosis in breast cancer and might serve as a tumor marker. PMID: 22982673
7. Significantly greater creatine kinase carbonylation is associated with chronic obstructive pulmonary disease PMID: 16166745
8. Because creatine kinase temporally buffers ATP, these observations support the hypothesis that a deficit in myofibrillar energy delivery contributes to chronic heart failure pathophysiology in human left ventricular hypertrophy. PMID: 16952984
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亞細胞定位：

Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
蛋白家族：

ATP:guanido phosphotransferase family
數據庫鏈接：

HGNC: 31736

OMIM: 123290

KEGG: hsa:1159

STRING: 9606.ENSP00000406577

UniGene: Hs.654988

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